运用腰池腹腔分流术与脑室腹腔分流术治疗交通性脑积液患者的Meta分析.docVIP

运用腰池-腹腔分流术与脑室-腹腔分流 术治疗交通性脑积液患者的Meta分析 吕东钟东张福安李炯黄浩洋杜伟夏海坚 重庆医科大学附属第一医院神经外科 目的探讨脑室-腹腔（V-P）和腰池-腹腔（L-P）分流术治疗交通性脑积水患者 的疗效。方法采用计算机检索PubMcdx Web of Science、Scopuss、Karger、 EBSCO+MEDLINE、OVID、EMBASE、中国知网、中国生物医学全文库、万方、维普 数据库，查出1990-2016年上述数据库所收录的有关L-P和V-P分流术治疗交通 性脑积液的相关文献，并运用STATA12. 0软件进行Meta分析。结果交通性脑积 液患者予以L-P分流手术的成功率明显高于V-P分流术（P〈0.05），术后感染 率、分流系统梗阻率及总并发症发生率较低（P0. 05）,两组的分流欠佳率差异 无统计学意义（P〉0.05）。结论L-P分流术在交通性脑积液患者中值得推荐， 由于证据质量较低，需要更多高质量的原始研宄来弥补该研宄的不足。 关键词： 交通性脑积液;腰池-腹腔分流术;脑室-腹腔分流术;Meta分析; 吕东（1989-）,硕士，主耍从事神经外科工作。 钟东， : zhongdongdp@sina. com。 2017-05-04 基金：国家临床重点专科建设项0 （财社[2011]170号） Application of lumboperitoneal shunt and ventriculoperitoneal shunt in treatment of patients with communicating hydrocephalus:a Meta analysis Lyu Dong Zhong Dong Zhang Fuan Li Tiong Huang Haoyang Du Wei Xia Haijian Department of Neurosurgery， First Affiliated Hospital of Chongqing Medical University; Abstract： Objective To investigate the effect of lumboperitoneal (L-P) shunt ancl ventriculoperitoneal (V-P) shunt for treating the patients with communicating hydrocephalus. Methods The databases of PubMed, Web of Science, Scopuss, Karge, EBSCO+MEDLINE, OVID, EMBASE, CNKI, CBM disc databases, Wanfang databases, Weipu databases were retrieved by computer. The relevant literatures about L-P shunt and V-P shunt for treating communicating hydrocephalus included in these databases during 1990-2016 were collected and performed the meta analysis by using the STATA12. 0 software. Results The success rate of L-P shunt in treating communicating hydrocephalus was apparently higher than that of V-P shunt (P0. 05) . Moreover, postoperative infection rate, obstruction rate of shunt system and total postoperative complications rate in L-P shunt were apparently lower than those of V-P shunt (P0. 05)，However, there was no statistical difference in shunt poor rate between L-P shunt and V-P shunt (P0.05) . Conclusion I厂P shunt is worth recommending.But due to lower quality of the evidences, it is needed more high q