ct导下经皮微波消融作为进展期非小细胞肺癌的维持治疗新手段-肿瘤学专业毕业论文.docxVIP

山东大学博士学位论文 CONTENTS Abstract in Chinese ·1 Abstract in English-·_-···· ·····-·-·······················-········································································-······················‘ ···-····_-··’4 Abbreviating Words‘·····-·····-_·-······················-··························-·············_············································-··················-····--·-‘8 Text l Introduction 一1 0 2 Materials and Methods 2．1 Inclusion and Exclusion Criteria- ·12 2．2 Course of treatment 2．2．1 First—line treatment 1 3 2．2．2 MWA procedure 14 2．3 Follow-up and treatment assessment ’1 8 2．4 Statistical Analysis ‘2 1 3 Results 3．1 Complications ’22 3．2 Local efficacy ’23 3．3 Survival “23 4 Discussions 25 5 Conclusions······························ ······ ·· · ·- 29 6 Appendix’···········································-················· · ··-·· ·· ·· ··_-· ·····················-··········。 ···‘· · ·· ’30 7 Reference ···· ··_···· ····················································· · · ·- 43 Acknowledgements‘········-··_····--········_-··-··-·········_··-·····-····_·-_····_······_······_···-·······_········-·-··-_··-···--··--······················_·······-·’50 Published Articles During the MD’····-····_··‘ ·-····· ·‘·····‘ ·····。·····-·-····_··^···-_··········-·····-···········-_···‘·。-··-····_·-····‘5 1 Dissertation appraisement-····················································································-············-··-·-··-··············‘·‘·············’52 Articles in English Articles in English No．1 ”53 Articles in English No．2’········_············_·········-··_·_··············· · ·· · ···························································‘74 万方数据  山东大学博士学位论文 摘要 目的：肺癌是世界范围内癌症的主要死因，中国是世界第一肺癌大国，肺癌居我 国癌症发病率和死亡率的首位。非小细胞肺癌占全部肺癌病例的89％。进展期非 小细胞肺癌失去了根治性手术的机会，目前以系统化疗为主要治疗手段。然而， 传统一线治疗已经达到了