后基因条组时代的系统生物学 吴家睿.pptVIP

Comparison with growth phenotypes showed that experimental and computational outcomes agreed in 10,828 (78.7%) Each case is categorized by comparison type (Exp/Met/Reg), high-throughput phenotyping array data (Exp) predictions for the E. coli network with regulatory constraints (Reg) predictions for the E. coli network ignoring such constraints (Met) Results are listed as ‘+’ (predicted or observed growth), ‘-’ (no growth) or ‘n’ (for cases involving a regulatory gene knockout not predictable by the Met model). a fraction of agreement (FA) between regulatory model predictions and observed