分析特发性黄斑前膜的黄斑形态与视力的相关性.pdfVIP

福建医科大学硕士学位论文 与Group3 的MFT 差异具有统计学意义（P=0.02），余差异无统计学意义，可以 认为 Group2 和 Group3 MFT 的分布不同。MFT 与 LogMAR 具有显著正相关 （r=0.352，P=0.013，＜0.05），即黄斑中心小凹神经视网膜层越厚，LogMAR 越大，亦最佳矫正视力越差。CFT 与 LogMAR 具有显著正相关 （r=0.478， P=0.001），即黄斑中心凹 1mm 直径范围内神经视网膜层的平均厚度越厚， LogMAR 值越大，亦最佳矫正视力越差。当AN≥22°，AN 与LogMAR 具有显著 正相关（r=0.633，P=0.005）；当AN＜22°时，AN 与LogMAR 具有显著负相关 （r=-0.629），即AN 偏离22°越远，LogMAR 越大，最佳矫正视力越差。当AT ≥22°，AT 与LogMAR 具有显著正相关（r=0.611，P=0.012）；当AT＜22°时， AT 与LogMAR 具有显著负相关（r=-0.582，P0.05），即AT 偏离22°越远， LogMAR 越大，最佳矫正视力越差。 结论 用频域光学相干断层扫描仪可定量检查特发性黄斑前膜患者的CFT、MFT、 AT 及AN，而这些测量值可用于评估特发性黄斑前膜与对视力的损害程度。对 于合并特发性黄斑前膜的老年性白内障患者拟行白内障摘除手术，术前评估手 术预后，AN、AT、MFT 可以发挥其独特的作用。 关键词 特发性黄斑前膜，频域光学相干断层扫描，神经视网膜厚度，黄斑中心凹斜 坡角度，最佳矫正视力 3 福建医科大学硕士学位论文 ABSTRACT PURPOSE The purpose of this study is to evaluate the macular morphological changes associated with idiopathic epiretinal membrane (IERM) using high density optical coherence tomography (HD-OCT) ,as they correlate with best corrected visual acuity(BCVA). METHODS 62 eyes of 52 patients who were diagnosed as IERM and under went phacoemulsification with intraocular lens implantation from May 2013 to December 2014 at Fujian Provincial Hospital were recruited. We carried out the detailed ophthalmologic examination for all patients, including BCVA, anterior segment, ratina and macular scan by OCT. We acquired several paratemers from OCT including:1)Macular foveola thickness(MFT)was measured by placing the calipers from the inner retinal surface to the retinal pigment epithelial layer at the center of the fovea; 2)Angle of macular foveal slope was measured by placing the calipers at the inner retinal surface at the center of the fovea,and then made