基于咔唑母体的双光子荧光探针的设计、合成及性能研究-高分子化学与物理专业论文.docxVIP

优秀毕业论文 精品参考文献资料 ABSTRACTABSTRACT ABSTRACT ABSTRACT In recent years，fluorescent probe，with high sensitivity and selectivity,is regarded as an effective biological detective tool，because it is able to conduct real．time detection and easy to operate·Most fluorescent probes being reported S0 far are single photon fluorescent probes． There are many drawbacks due to the fact that single photon fluorescent probes are activated by short wavelength．For instance，single-photon fluorescent probes are highly likely to give rise to photo damage，photo-bleaching and background color．In consequence，in order to overcome the drawbacks of single photon fluorescent probes，it is necessary for US to seek two-photon fluorescent probes with larger absorption cross．section and more sensitive detection，which is activated by long wavelength，is capable of being used in cells and is equipped with higher fluorescence quantum yield．Hypochloric acid，one of the important reactive oxygen species in organisms，is endowed with oxidability,which casts tremendous influences upon organisms and is widely used in daily life． excessive hypochloric acid will causes some diseases，such as cancel．Gold is a kind of precious medal，which can be used to make currency,jewelry and accessories．Moreover,gold ion，which is anti-inflammatory,Can be used to make medicine for arthritis and cancer．Even though gold ion call be used in SO many ways，we should also attach importance to its formidable toxicity, since it Can combine with DNA intimately,doing damage to liveq kidney and the nervous system·As a result，we ought to lay control over the content of gold ions．Cu is a significant transitional metals， only secondary to Fe and Zn， and plays an indispensable role in maintaining the normal function of organisms．Even though there are few Cu2+ions in organisms，lack of Cu2+ions will cause disturbance to organisms growth process．Similarly, excessive Cu2+ions will also intoxicate organisms．In consequence，it has been an importa