稀土抗菌效应及应用的研究进展-微生物学报.PDFVIP

微生物学通报 JAN 20, 2009, 36(1): 90~96 Microbiology © 2009 by Institute of Microbiology, CAS tongbao@ 专论与综述 稀土抗菌效应及应用的研究进展 1 1 1∗ 1 2 陈爱美 施庆珊 欧阳友生 陈仪本 谭绍早 (1. 510070) (2. 510632) 摘 要: 稀土元素具有多种生物效应, 除了对农作物的增产作用外, 在医药方面还具有抗菌的作 用, 近年来, 不少学者针对稀土元素的抗菌效应展开了相关的研究。本文介绍了稀土在抗菌领域 的研究及应用, 包括稀土化合物对微生物生长的Hormesis 效应、稀土化合物与抗生素的协同作用、 稀土配合物的合成、以及稀土在抗菌材料上的应用等几个方面的内容, 并对稀土化合物及其配合 物的抗菌机理进行了探讨, 最后, 展望了稀土化合物及配合物在抗菌领域的应用前景及研究重 要性。 关键词: 稀土元素, Hormesis 效应, 抗菌活性 Progress in Antimicrobial Activity and Application of Rare Earths CHEN Ai-Mei1 SHI Qing-Shan1 OUYANG You-Sheng1* CHEN Yi-Ben1 TAN Shao-Zao2 (1. Guangdong Institute of Microbiology, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, Guangdong 510070, China) (2. Department of Chemistry, Jinan University , Guangzhou, Guangdong 510632, China) Abstract: Rare-earth elements are characterized with their biological effects on some organisms. Besides the increase production effect in agriculture, rare-earth elements also have antimicrobial effect in clinic. Re- cently, the antimicrobial effect and mechanism of rare-earth elements are under investigation by some schol- ars. This paper summarized the antimicrobial activity and application of rare earth compounds and com- plexes, including Hormesis effect of rare-earth elements to some microorganism, synergi