附件I实验中动物安乐死时机及准则.PDFVIP

附件 I實驗中動物安樂 死時機及準則 Appendix I Criteria for Euthanasia of Animals Used in Research Teaching 立屏東科技大學（NPUST ）動 物實驗申請 表附件（Animal Use Protocol Appendix ）- 20 12年7月制訂版 背景 Background 實驗中動物安樂 死時機及準則由 IACUC制訂，主要在規範尚未完成實驗之動物 發生實驗所引起或非預期症狀，而必須將動物安樂死之狀況。 These criteria have been established by the Institutional Animal Care and Use Committee, which recognizes that euthanasia is sometimes necessary prior to the scheduled end of a study, either because of unanticipated complications, or because of the protocol itself. 準則 Criteria 此準則適用於所有實驗中或未實驗之動物。除了 IACUC已審查同意之情 形（如： 實驗引起之預期中症狀且能使動物痛苦程度減至最低 ），否則只要符合下列任 項情況即需 將動物安樂死。 These criteria apply to all animals on experimental protocols, whether manipulated or not. Fulfillment of one criterion can constitute grounds for euthanasia. Exceptions are permitted only if approved by the Committee as part of the protocol review process (i.e. the clinical signs listed below are expected as part of the experiment and appropriate measures are taken to minimize pain or discomfort in the animals). 1. 體重減輕 Weight loss: 體重減輕達 20-25％ ，或是動物 出現惡病質或消耗性症候時。 *非生長期動物體重減輕可依據動物剛進動物房之體重或 平均年齡體重 為依 據 。 生長期之動物體重或許不會下降 ，但若無法正常增重 ，仍應判為體重減輕 。 Weight loss of 20-25% (depending on attitude, weight recorded at time of arrival, and age: growing animals may not lose weight, but may not gain normally) or if not measured, characterized by cachexia and wasting syndrome. 1 PDF 檔案使用pdfFactory Pro 試用版本建立 2.喪失食慾 Inappetance: 小型齧齒類動物完 全喪失食慾達24 小時或食慾不佳 （低於正常量