源于整体观思想的中药质量评价方法研究概述.docxVIP

中国中药杂志 2015Q6(40), 1027」031 DOI: 10.4268/cjcm源于“整体观”思想的中药质量评价方 法研究概述 姜华高原杨景明孟祥才 黑龙江中医药大学 辽宁医学院 辽宁富东制药有限 公司 导出/参考文献关注 分亨 收藏打印 摘要： 建立符合中药作用特点并能被国际社会认可的中药质量评价体系,是当前中药现 代化、国际化进程中迫切需要解决的一项艰巨任务。中药作用的整体性、组成成 分的多样性、作用靶点的复杂性、以及成分间相互作用的难以预测性，使得检测 单一活性成分的西药质控方法在中药中行不通。整体观思想是破解目前中药质控 碎片化，突破“找成分、测含量、订下限”模式的重要指导，突破单纯的“唯成分 论”，构建符合中药采、希I」、性、效、用特点的综合量化集成的评控模式。该文 从中药质量的本草属性、品种特性、化学特性、组效关系、组分结构关系等方面 对中药质量的评价模式进行了概述，对于真正把握中药质量内涵,科学评价中药 质量优劣具有积极的参考价值。 关键词： 整体观;中药质量;评价方法; 作者简介：孟祥才，博士生导 师，Tel E-mail: HYPERLINK mailto:mengxiangcai000@ mengxiangcai000@ 作者简介:姜华，博士研究生,Tel: E-mail:qq. com 收稿日期：2014-11-03 基金：辽宁省教育厅科学技术研究项目（L2013330） Overview of traditional Chinese medicine quality evaluation method based on overall research JIANG Hua GAO Yuan YANG Jing-ming MENG Xiang-cai Heilongjiang University of Chinese Medicine; Liaoning East Phmnaceutical Co. 丄td.; Abstract： The estciblishment of quality evaluation of traditional Chinese medicine system that not only accords with Chinese medicine function charactcristics but alsois recognized as international medical circles, is an arduous task in urgent need of solving the current modernization of traditional Chinese medicine in the process of internationalization. It is difficult to evaluate atraditional Chinese medicineby detection of single active components in traditional Chincscmcdicincwiththc western medicine quality controlmcthod due to theoverall effects of traditional Chinese drugs, the components of the overall diversity, targets, and the complexity of the interaction between components of unpredictable, make the. Long term since, domestic and foreign scholars continue to explore and put forward a series of quality evaluation of traditional Chinese medicine to promote the development of traditional Chinese medicine. This article summarizedthe related academic ideas and developments to,providea new thought and perspective for the quality control of traditional Chinese medicine. Keyword： overall conce