tl胶囊对中风后遗症的药效及机理研究中药学专业论文.docxVIP

成都中医药大学博士学位论文cerebral 成都中医药大学博士学位论文 cerebral hemorrhage rats．The effect ofTLC may be related to increase ofthe number of macrophages，neuron and the Nissl’s body of neuron in the ICH．②TLC can protect the structures of brain tissue in experimental cerebral ischemia rats．The effect of TLC may be related to increase of the number of neuron and the Nissl’s body of neuron in the CI．③Effect of TLC on cerebral ischemia-reperfusion injury is closely related to the acceleration of cleaning oxygen derived free radicals，increasing SOD activily、reducing LPO content，MDA content．④TLC obviously increased the activities of Na+。K+-ATPase，Ca2+_ATPase．⑤The effect of TLC may be related to the decrease ofNOS，iNOS activities，and NO content in brain tissue． Key Words：TL capsule；stroke sequela；intracerebral hemorrhage；cerebral ischemia； phannacodynamic action；mechanism 成都中医药大学博士学位论文英文缩略词 成都中医药大学博士学位论文 英文缩略词 缩写 英文全名 中文译名 从 arachidonic acid 花生四烯酸 ACA anterior cerebral artery 大脑前动脉 Adr adrenalin 肾上腺素 ADP adenosine一5-diphosphate 二磷酸腺苷 AIS acute ischemia syIldrome 急性缺血性卒中 ATPase adenosine triphosphatase 三磷酸腺苷酶 BBB blood brain barrier 血脑屏障 CCA corrmaorhcarotid artery 颈总动脉 CBF cerebral blood flow 脑血流量 CI cerebral ischemia 脑缺血 CIRI cerebral isehemia reperfusion injury 脑缺血再灌注损伤 CGRP calcium gene—related pepfide 降钙素基因相关肽 DND delay neuronal death 延迟性细胞死t_ eNOS endothelial CONstitutive NOS 内皮起源一氧化氮合成酶 ECA external carotid artery 颈外动脉 ET endothelin 内皮素 EAA excitatory amino acids 兴奋性氨基酸 GABA Aminobutyric Acid Y一氨基丁酸 GLU glutamic acid 谷氨酸 HI hemorrhagic infarction 出血