置管溶栓与传统外周静脉溶栓治疗下肢深静脉血栓对比研究.PDF

104 ● 论著 ● 《中国医学前沿杂志 （电子版）》2015 年第7 卷第12 期 置管溶栓与传统外周静脉溶栓治疗下肢 深静脉血栓对比研究 龚秸明，杨其鹏，卫志庆 （南京医科大学第二附属医院　血管外科，南京　2 10011） 【摘要】目的 比较置管溶栓与传统外周静脉溶栓治疗下肢深静脉血栓的临床效果。方法 选取本院 2013 年8 月至2014 年8 月收治的100 例采用置管溶栓联合低分子肝素和尿激酶治疗的下肢深静脉血 栓患者为观察组，选取本院同期收治的100 例仅采用低分子肝素和尿激酶治疗的下肢深静脉血栓患者 P ＜0.05 ）。 为对照组，比较两组患者的治疗效果。结果 观察组患者治疗总有效率显著高于对照组 （ P 观察组患者疼痛消失时间、肿胀消失时间、住院时间均短于对照组，尿激酶用量少于对照组 （ ＜0.05 ）。 P 观察组患者治疗后健/ 患肢大腿和小腿的周径差均明显小于对照组 （ ＜0.05 ）。观察组患者深静脉通 P 畅率、病理性反流率、肢体再肿胀率均低于对照组 （ ＜0.05 ）。两组患者并发症发生率比较无显著差 P 异 （ ＞0.05 ）。结论 置管溶栓联合低分子肝素和尿激酶治疗下肢深静脉血栓效果较好，疗程短，静 脉通畅率高，并发症少，值得临床推广。 【关键词】置管溶栓；低分子肝素；尿激酶；下肢深静脉血栓 A comparative study of catheter­directed thrombolysis and traditional peripheral intravenous thrombo­ lysis in the treatment of lower extremity deep venous thrombosis GONG Jie-ming, YANG Qi-peng, WEI Zhi-qing (Department of Vascular Surgery, The Second Hospital of Nanjing Medical University, Nanjing 210011, China) Corresponding author: WEI Zhi-qing, E-mail: medvip@126.com Abstract Objective To compare the clinical effect of catheter-directed thrombolysis and traditional 【 】 　 peripheral intravenous thrombolysis in the treatment of lower extremity deep venous thrombosis. Method　 100 patients with lower extremity deep venous thrombosis from August 2013 to August 2014 were collected as observation group, who were treated with catheter-directed thrombolysis combined with low molecular heparin and urokinase therapy, 100 cases of lower extremity deep venous thrombosis patients treated with low molecular heparin and urokinase were selected as control group at the same time, the therapeutic effective of the two groups were compared. Result　The total