基于MHC调控的免疫公式发现算法-软件学报.PDFVIP

ISSN 1000-9825, CODEN RUXUEW E-mail: jos@ Journal of Software , Vol.19, No.3, March 2008, pp.650−662 DOI: 10.3724/SP.J.1001.2008.00650 Tel/Fax: +86-10 © 2008 by Journal of Software . All rights reserved. ∗ 基于 MHC 调控的免疫公式发现算法 1+ 2 2 胡 珉 , 吴耿锋 , 杨 晶 1(上海大学 悉尼工商学院,上海 200072) 2(上海大学 计算机工程与科学学院,上海 200072) MHC Regulation Based Immune Formula Discovering Algorithm 1+ 2 2 HU Min , WU Geng-Feng , YANG Jing 1(Sydney Institute of Language and Commerce, Shanghai University, Shanghai 200072, China) 2(School of Computer Engineering and Science, Shanghai University, Shanghai 200072, China) + Corresponding author: Phn: +86-21ext 8509, Fax: +86-21 E-mail: minahu@ Hu M, Wu GF, Yang J. MHC regulation based immune formula discovering algorithm. Journal of Software, 2008,19(3):650−662. /1000-9825/19/650.htm Abstract : Aiming at the difficulty in good segments of the formula to be inherited in formula discovering using gene expression programming (GEP), this paper proposes an innovative immune formula discovering algorithm (IFDA), which is actually inspired by MHC (major histocompatibility complex) regulation principle of immune theory. In IFDA, the formula are mapped as a tree structure and transformed into both constant and variation section of antibody with a depth-first mechanism while its fragment is encoded into the MHC. By the feature of MHC regulation, IFDA mines the dataset to discover the proper formula very quickly. Many data are benchmarked for verifying the perfo