植物多糖分离纯化工艺研究进展-中国中医药信息杂志.PDF

·136· Chinese Journal of Information on TCM May 2018 Vol.25 No.5 植物多糖分离纯化工艺研究进展 肖瑞希，陈华国，周欣 贵州师范大学，贵州省山地环境信息系统与生态环境保护重点实验室， 贵州省药物质量控制及评价技术工程实验室，天然药物质量控制中心，贵州 贵阳 550001 摘要：植物多糖因具有抗肿瘤、抗病毒、抗氧化等生物活性和多种药用价值，近年已广泛应用于生命科学 等研究领域。由于植物多糖相关研究受其油脂、蛋白质、色素等杂质影响较大，故除杂质、分离纯化技术是该 领域研究开展的重要前提。本文对近年来植物多糖的脱脂、除蛋白、除色素等分离纯化方法技术的研究现状进 行总结，为植物多糖的深入研究与开发提供参考。 关键词：植物多糖；除杂质；分离纯化；综述 DOI：10.3969/j.issn.1005-5304.2018.05.034 中图分类号：R284.2 文献标识码：A 文章编号：1005-5304(2018)05-0136-05 Research Progress in Separation and Purification of Plant Polysaccharides XIAO Rui-xi, CHEN Hua-guo, ZHOU Xin Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Engineering Laboratory for Quality Control ＆Evaluation Technology of Medicine, Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang 550001, China Abstract: In recent years, because plant polysaccharides are with anti-tumor, anti-virus, anti-ulcer, anti-oxidation and other unique biological activity, a variety of medicinal values have been frequently applied in the field of life sciences research. However, because plant polysaccharides research is limited by its fat, protein, pigment and other impurities, technology of impurities and separation and purification are important premise of research development in this field. This article mainly summarized the recent research on the methods of impurities, separation and purification of plant polysaccharides, which provided a reference for the further research and development of plant polysaccharides. Keywords: plant polysaccharide; impurity removal; separation and purification; review 多糖广泛存在于动植物中，它通过超过 10 个糖 1 多糖除杂质 苷键连接不同或相同的单糖而形成，具有抗肿瘤[1]、