江西省甲型病毒性肝炎流行病学现状及重点地区甲肝疫苗强化免疫流行病学效果研究-公共卫生专业论文.docxVIP

Ab Abstract Ab Abstract PAGE PAGE IV PAGE PAGE V ABSTRACT Objective: To analyze EPIDEMIC characteristics and trends of hepatitis A from 1999 to 2014 in Jiangxi Province, find out hepatitis A Immunization coverage rate and Supplementary immunization effect in key areas of Jiangxi province ,and study the relationship between them. To explore scientific and effective hepatitis A prevention strategy, evaluate objectively of the effect of hepatitis A vaccination; explore and develop the best immunization program further ,to reduce the incidence of hepatitis A . Methods: Epidemiological data of hepatitis A from 1999 to 2014 obtained from disease reporting system in Jiangxi Province and demographic data obtained from statistical yearbook in statistics bureau of Jiangxi Province were analyzed by descriptive epidemiological method, using SPSS18.0. To carry out mass vaccination of hepatitis A attenuated live vaccine for chi-ldren from 18-month-old to 12-year-old who do not have the history of hepatitis illness and hepatitis A vaccine(Children born from January 1, 1997 to April 30, 2007 ) in Yudu, Ruijin, Wanan, Yuanzhou, Wanzai in 2009.To collect and analyze vaccination data and hepatitis A incidence from 2003 to 2014 in key areas using descriptive epidemiological method . The hepatitis A vaccination rates hepatitis A incidence were analyzed by SPSS18.0 . Results: The yearly average incidence rate of hepatitis A is 6.7302 /lakh in Jiangxi province from 1999 to 2014, the overall incidence of hepatitis A had declining trend (χ2 = 30956.867, P 0.001). The yearly average incidence rate of hepatitis A from 1999 to 2007 is higher than the yearly average incidence rate from 2008 to 2014, the difference was significant statistically by the statistical tests（χ2=319997.944，P0.001）。 The Hepatitis A incidence is not seasonal different obviously in Iiangxi province from 2001 to 2014. There are more Hepatitis A cases from march to may. The yearly ave