心力衰竭心脏再同步（CRT)治疗PPT课件.pptVIP

* * * Cardiac Resynchronization is achieved through atrial based, biventricular pacing. Standard pacing leads are placed in the right atrium and right ventricle. A specially designed left ventricular pacing lead is passed through the coronary sinus and into a tributary of the Great Cardiac Vein. Atrial based pacing is performed through both ventricular leads simultaneously and can be programmed unipolar or bipolar if either ventricular lead is a bipolar lead. InSync was developed to provide true cathodal pacing to two ventricular leads simultaneously. InSync employs Medtronic’s longest lived battery with Medtronic’s lowest current-drain circuit technology. The expanded connector allows direct connection to one atrial and two ventricular leads without the need for adapters or splitters. * Main purpose: Show that a large number of patients have been studied in completed and ongoing randomized controlled studies of CRT. Use in conjunction with previous slide. Key messages: Nearly 3000 patients have been enrolled in randomized controlled clinical trials presented to date. When CARE-HF, another landmark trial assessing mortality and hospitalization, is reported, close to 4,000 patients will have been studied. * Almost everybody will have heard about the InSync Study. Ongoing, multicentre, prospective, controlled study to evaluate cardiac resynchronization In patients with dilated cardiomyopathy, inter- and intra-ventricular conduction disturbances (IVCDs), and congestive heart failure. Assess clinical effects of therapy in defined patient population. Evaluate safety and performance of the InSync system, including special pacemaker and left ventricular lead. Establish the feasibility of implanting the InSync system. Substudy objective: Assess whether baseline NYHA functional class influences clinical outcomes: 6 minute walk distance, Quality of Life, NYHA Functional class * * * * * * Results will be presented in detail by Berthold Kramm. * * * * * Resynchroni