酒精性肝病164例临床分析-内科学专业论文.docxVIP

酒精性肝病164例临床分析硕士研究生： 酒精性肝病164例临床分析 硕士研究生： 王丽霞 指导教师： 赵钢 教授 专业名称： 内科学 摘 要 目的：对我院10年来收治的164例酒精性肝病患者进行临床资料 分析，分析研究其发病情况及临床特点，以进一步提高对酒精性肝病 的认识，为早期发现、早期治疗酒精性肝病提供依据。 方法：根据饮酒史，临床表现，肝功能检查，影像学检查，按照 2002年10月南京会议制定的酒精性肝病临床诊断标准，将164例患者 的数据进行统计学分析，做出临床分析和讨论。 结果：酒精性肝病发病有增多趋势，尤其酒精性肝硬化逐年增多， 41～50岁为好发年龄。AST／ALT、GGT、TBIL及TG对酒精性肝炎的 诊断有重要意义。剐G比值随疾病进展丽降低。慢性病毒性肝炎的饮 酒者预后差，更易发展为肝癌。死亡的主要原因是肝硬化的晚期并发 症。 结论：酒精性肝病病情和预后与长期饮酒史(包括饮酒量、饮酒时 间1有关。发病有逐年增多、年轻化趋势。对于有饮酒嗜好的病人，应 定期对AST／ALT、GGT、TBIL及TG等生化指标监测，从而争取早期 诊断、早期治疗、改善预后。 关键词：酒精性肝病；AST／ALT：GGT Clinical Clinical analysis of 1 64 patients with alcoholic liver disease Postgraduate：Wang Lixia Instructor：Professor Zhao Gang Major：Internal medicine Abstract objeetive：To analyze the clinical data in 164 in-patients with alcoholic liver disease(ALD)in the First Affiliated Hospital of Dalian Medical University in recent 1 0 years，and to study the morbidity and clinical characteristics，so as to understand ALD in a greater extent and to provide theoretical basis for an early diagnosis and treatment． Methods：The clinical data of l 64 patients with ALD were analyzed statistically, which included history of alcohol intake． clinical manifestations，liver function tests and radiology results．The diagnosis was based on the ALD diagnosis standards．in Nanjing Meeting held in-October of2002． Results：The morbidity ofALD，especially alcoholic liver cirrhosis is increasing annually．Those at forty to fifty are susceptible． Measurements of AST／AL工GGT’TBIL and TG are of important significance in diagnosis of alcoholic hepatitis，while the decrease of A／G ratio indicates the progression of disease．Those with chronic viral hepatitis have poor prognosis and would be more likely to develop into liver cancer．The main causes for death are the complications at 1ate stage of liver cirrhosis． Conclusion：The severity and prognosis ofALD may be related to the long·term alcohol abuse history(including the amount and duration of drinking)．There is a tendency of increase annually and younger