蛋白质结西构与功能s.pptVIP

蛋白质结构与功能 (学习要点);VLSEGEWQLVLHVWAKVEAD VAGHGGDILIRLFKSHPETLEK FDRFKHLKTEAEMKASEDLKK HGVTVLTALGAILKKKGHHEA ELKPLAQSHATKHKIPIKYLEFI SEAIIHVLHSRHPGDFGADAQ GAMNKALELFRKDIAAKYKEL GYGG;Gly;6-2b;? 肽键以共振杂化形式存在;W2.4;W2.5;? 并非所有的?和?角都允许 ;Tab W2.1;4-4 (2nd);常有带负电的残基在N-末端与肽链结合以稳定螺旋偶极矩的正电荷 ~ N-末端积累了部分正电荷;R-侧链指向?-螺旋外侧 有利于减少立体障碍;6-11;b6-2;Parallel b-strand;polypeptide chain almost fully stretched out;? Protein 3-D structure: silk fibroin, a fibrous protein;AA 3 = Gly in Type II;6-13;? Collagen: a triple helix with a unique 2° structure;(cf. Fig. 3-17);Every 3rd AA is a Gly, and many of the remainings are Pro/