新生儿腹泻中轮状病毒性肠炎及继发性乳糖酶缺陷的发病情况及临床特点.docxVIP

新生儿腹泻中轮状病毒性肠炎及继发性乳糖酶缺陷的发病 情况及临床特点 钱爱民 (江苏省兴化市人民医院儿科225700) 【摘要】口的探讨新生儿腹泻屮轮状病毒性肠炎及继发性乳糖酶缺陷的发 病情况及临床特点。方法 我院2012年1月一12月门诊收治新生儿腹泻46例， 采用酶联免疫吸附法(ELISA)进行粪便轮状病毒抗原测定，对确诊为轮状病毒性肠 炎的患儿采用醋酸铅加氢氧化氨法检测粪便屮乳糖、pH值。对轮状病毒性肠炎 屮继发性乳糖酶缺陷的患儿，在综合治疗的基础上给予去乳糖饮食干预治疗。结 果46例新生儿腹泻患儿屮，经检测，确诊轮状病毒性肠炎患儿为36例。36 例轮状病毒性肠炎患儿屮继发乳糖不耐受者32例。应用综合治疗同时结合去乳 糖饮食干预治疗的患儿组，治疗的有效率，明显好于仍维持以前饮食习惯的患儿 组。结论 轮状病毒是引起新生儿腹泻的最常见病原，而轮状病毒肠炎患儿乳糖 不耐受的发生率很高。在新生儿腹泻的治疗中，应进行轮状病毒检测，对确诊为 轮状病毒性肠炎的患儿检测粪乳糖及pH ,早期发现继发性乳糖酶缺陷症，在综 合治疗的基础上给予去乳糖饮食干预治疗。 【关键词】新生儿腹泻轮状病毒性肠炎继发性乳糖酶缺陷 【屮图分类号】R722 【文献标识码】A 【文章编号】2095-1752 (2014) 17-0086-02 The incidenee and clinical characteristic of neonatal diarrhea rotavirus enteritis and sec on dary lactase deficie ncy Qian Aimin Department of Pediatrics Xinghua Peoples Hospital of Jiangsu provinee. 225700 【Abstract] Objective To investigate the clinical feature and neonatal diarrhea rotavirus en teritis and defect sec on dary lactase in cide nee. Methods In our hospital from 2012 January to December clinic treated 46 cases with neonatal diarrhea, by enzyme linked immunosorbent assay (ELISA) for stool rotavirus antigen assay, diagnosis of rotavirus enteritis in children with lead acetate and ammonium hydroxide method in detecting fecal lactose, pH. Rotavirus enteritis in children with secondary lactase deficient, based on a comprehensive treatment given to lactose diet intervention. Results 46 cases of neonatal diarrhea in children, tested, diagnosed in children with rotavirus enteritis of 36 cases. 36 cases of children with rotavirus en teritis sec on dary lactose intolerance in 32 cases. Applicati ons combi ned with comprehensive treatment of children with lactose diet intervention group, efficient treatment remained sign讦icantly better than the previous group of childre nfs eati ng habits. Conclusion Rotavirus is the most comm on cause of n ewbor n diarrhea caused by rotavirus en teritis, and lactose in tolerance is a high incidenee of. In the treatment of neonatal diarrhea, should be carried out in children w