基于网格的生物数据管理与访问服务研究计算机科学与技术专业论文.docxVIP

哈尔滨工业大学工学硕士学位论文 哈尔滨工业大学工学硕士学位论文 - - II - Abstract With biological research carried out at molecular level, in particular, with the research carried out at molecular level of the Human Genome Project, there are a mass of biological data produced which resulted in hundreds of biological databases created. There is a great deal of biological knowledge which can be extracted from the biological data. The key and prerequisite to conduct modern biological researches are how to organize and manage biological data efficiently, analyze and mine useful information from these databases. It is inevitable to adopt grid technologies to share biological data. This is because that the characters of biological data in our country, including geographically distribution, the differences in regional development, the heterogeneity in biological databases, the instability of the network infrastructure, and so on. This thesis focuses on the research on the data management and access in a biological data grid based on metadata. First of all, we abstract the biological data, and establish the classification technique of biological data according to their characters. The technique classifies all biological data into five categories. At the same time, we divide each category into multiple layers. This enables each database to be addressed with unified classification technique. On the basis of the classification technique, we define the metadata of biological data grid, design two-layered distributed metadata as well as the management model, and realize the organization and management of the metadata, all of these laid the foundation of access and management of data resource. Secondly, for the purpose of realizing the transparent access to biological data, we design biological data access model based on the metadata, which t akes data resource category as the foundation and constructs two-layered middleware for data access. The layer of data manipulation activity defines the mechanisms of da