鼻咽癌个体化后程同步放化疗的随机性分析.pdfVIP

放射反应而长时间中断放疗的情况。慢性放射反应还有待观察． 结论中晚期鼻咽癌的个体化治疗是一种能被绝大多数病人耐受、大幅 提高局控率的治疗方法。 【关键词】 鼻咽肿瘤／放射治疗；癌／放射治疗 Randomizedtrialontheindividualof therapy midorlate carcinoma． stagenasophawngeal Abstract Toevaluatetreatmenteffectsandtodetermine Objective factorsoftheindividual ofmidorlate prognostic therapy stage carcinoma． nasopharyngeal MethodsFromFeb．2003toMar．2005．221 with patientsprimary 55malesand66 nasophargealcarcinoma，1 females。were randomizedinto test andcontrol group(107cases) thetest had group(114cases)．Ingroup，allpatientscomputed scansbeforeand treatmentatthedoseof tomography during 30Gy TheGTV volumewascalculatedwiththethreedimentional were with radiotherapyplanningsystem．Allpatientsadministered ndividual onthebasisofboththeGIVvolumebefore therapy treatmentandthedifferencebetweentheGTvvolumebefore at of treatmentandthat treatmentthedose the during 30Gy．In were control patientstreatedconventionalradiation group，all by survivalrateswerecalculated therapy．The the usingKplan-Meier method．Thetestwasusedin log-rank comparison Results