一种新的ASL图像去噪方法研究-计算机工程与应用.PDF

Computer Engineering and Applications 计算机工程与应用 2014 ，50（1） 159 一种新的ASL 图像去噪方法研究 1 2 1 1 3 刘 灿 ，高燕华 ，喻 罡 ，徐效文 ，张 明 1 2 1 1 3 LIU Can , GAO Yanhua , YU Gang , XU Xiaowen , ZHANG Ming 1.中南大学 地球科学与信息物理学院，长沙 410083 2.陕西省人民医院，西安 710068 3.西安交通大学 第一附属医院，西安 710061 1.School of Geosciences and Info-Physics, Central South University, Changsha 410083, China 2.Shaanxi Provincial People ’s Hospital, Xi ’an 710068, China 3.First Affiliated Hospital of Medical College, Xi ’an Jiaotong University, Xi ’an 710061, China LIU Can, GAO Yanhua, YU Gang, et al. New Arterial Spin Labeling image denoising method research. Computer Engineering and Applications, 2014, 50 （1）：159-162. Abstract ：Arterial Spin Labeling （ASL ）MR images suffer from low SNR . In order to achieve adequate high image quality, it is necessary to execute experiment a number of times repeatedly. 3D Gaussian filter is widely in clinical use but the fil- ter effect is not good enough. A new ASL image denoising algorithm based on Non-Local Means （NLM ）denoising meth- od is proposed. The new denoising method uses region similarity weight to decrease SNR and increases the accuracy of Cerebral Blood Flow （CBF ）map. The results of CBF maps indicate that the CBF map obtained by the proposed method is more close to the real result than the Gaussian smoothing, which realizes the goal of obtaining accurate CBF map in the case of less repeated times. Key words ：Non-Local Means （NLM ）; Gaussian filtering; Arterial Spin Labeling（ASL ）; image denoising 摘 要：动脉自旋标记（ASL ）MR 图像信噪比低，需要重复采集多次以获得高质量的血流（CBF ）图。临床中通常使 用3D 高斯滤波降低噪声但效果不佳。鉴于此，提出了新的基于非局域均值滤波（NLM ）的ASL 图像去噪方法，利用 图像内部块相似度加权，降低噪声并提高血流图的计算精度。实验证明：与高斯滤波的结果比较，采用新方法得到 的血流图和真实结果更接近，实现了在较少采集次数的情况下，得到精确的血流图像的目标。 关键词：非局部均值方法（NLM ）；高斯滤波；动脉自旋标记（ASL ）；图像去噪 文献标志码：A 中图分类号：TP391 ；TN911.73 do