桂枝加葛根汤对颈椎病家兔模型血浆内皮素(ET)、降钙素基因相关肽(CGRP)含量的影响-中医骨伤科学专业论文.docxVIP

万方数据 万方数据 硕士学位论文原创性声明 本人所呈交的硕士学位论文，是在导师黄俊卿教授的指导下，独立进行科学研究工作所取得的 成果。除文中已特别加以注明引用的内容外，论文中不包含任何其他个人或集体已经发表或撰写过 的研究成果。对本文的研究做出重要贡献的个人和集体，均已在文中以明确方式标明并致谢。本人 完全意识到本声明的法律结果由本人承担。 特此声明。 论文作者（签名）： 年 月 日 硕士学位论文使用授权声明 本人已完全了解河南中医学院有关保留、使用硕士学位论文的相关规定，同意学校保留或向国 家有关部门、机构送交本学位论文的复印件和电子版，允许论文被查阅或借阅。本人授权河南中医 学院可以将本论文的全部或部分内容编入有关数据库进行检索，可以采用影印、缩印或其他复制手 段保存、汇编本论文（注：保密论文在解密后适用本授权声明）。 特此声明。 论文作者（签名）： 导师（签名）： 年 月 日 年 月 日 目 录 摘要 ·························································································· 1 Abstract 2 前言 ·························································································· 4 材料与方法 ················································································ 6 1 实验材料 ·················································································· 6 2 实验步骤与方法 ········································································ 6 结果 ·························································································· 9 理论探讨 ···················································································· 11 1 中医学对颈椎病的认识与研究······················································· 11 2 现代医学对颈椎病的认识与研究 ···················································· 11 3 导师学术思想 ··········································································· 16 4 桂枝加葛根汤的作用及作用机制探讨 ·············································· 17 结论 ·························································································· 21 致谢 ·························································································· 22 参考文献 ···················································································· 23 附录 1：文献综述 ········································································· 25 附录 2：研究所期间发表论文 ·························································· 35 摘 要 目的：观察桂枝加葛根汤 对家兔颈椎病动物模型血浆内皮素（ ET）、降钙素基因 相关肽（CGRP）细胞因子的影响，并对颈椎病的作用机理进行探讨。 方法：取健康雄性家兔 50 只，按随机分组法分为正常组(Ⅰ)、模型对照组(Ⅱ)、 颈复康颗粒对照组(Ⅲ)、桂枝加葛根汤粒剂高剂量组(Ⅳ)、桂枝加葛根汤粒剂低剂量 组(Ⅴ)，每组 10 只。参照蹲坐