苦参联合动脉栓塞治疗原发性肝癌的临床效果观察-肿瘤药学.PDF

肿瘤药学 2014 年 6 月第 4 卷第 3 期　Anti-tumor Pharmacy, June 2014, Vol. 4, No. 3 - 229 - ●中医中药● 苦参联合动脉栓塞治疗原发性肝癌的临床效果观察 易彦博 ，谢开汉，刘歆春 ，白　剑* （长沙市中心 医院 普外科 ，湖南 长沙，4 10000 ） 摘要：目的　评估苦参联合动脉栓塞治疗原发性肝癌的临床效果和安全性。方法　以我院 2011 年 2 月至 2011 年 6 月收治的第一次行介入治疗的 73 例原发性肝癌患者为研究对象，随机分 A、B 两组，分别以苦参联合碘油 (A 组 ) 和碘油 (B 组 ) 进行肝动脉栓塞术。观察和比较两组肿瘤缩小率、远期生存状况及术后不良反应的发生情况。 结果　栓塞治疗后 A 组的肿瘤缩小率、治疗间隔周期、生存率均高于对照组，而不良反应率的差异无统计学意义。 结论　苦参联合碘油栓塞治疗原发性肝癌可有效提高肿瘤缩小率及远期治疗效果，且不增加不良反应发生率。 关键词：苦参；动脉栓塞；原发性肝癌；临床疗效 中图分类号：R735.7　文献标识码 ：A　文章编号：2095-1264（2014）03-0229-04 doi：10.3969/j.issn.2095-1264.2014.046 Clinical Effects of Sophora Combined Arterial Embolization on Hepatocellular Carcinoma YI Yanbo, XIE Kaihan, LI U Xinchun, BAI Jian* (Dep artment of General Surgery, Changsha Central Hosp ital, Changsha, Hunan, 410000, China) To evaluate the clinical effects of Sophora combined with TAC for hepatocellular carcinoma patients. Abstract: Objective Methods Seventy-three patients with primary hepatic carcinoma were randomly divided into two groups. Sophora combined with lipiodol (group A) and iodized oil (group B) were used through hepatic artery. Adverse reactions were observed after the surgery, and the rate of tumor shrinkage and long-term survival were observed. Results After treatment, group A showed better results in aspects of interval period, rate of tumor shrinkage and survival rate than group B, while had no significant statistical difference in the rate of adverse reactions with group B. Conclusion Sophora combined with lipiodo for primary liver cancer does not increase the incidence of adverse r