加味芍药甘草汤治疗慢性腰肌劳损的临床拆方研究-中医外科学专业论文.docxVIP

— — PAGE 1— 摘 要 加味芍药甘草汤治疗慢性腰肌劳损的临床拆方研究 唐欣荣 导师：吕发明教授 摘 要 目的：观察加味芍药甘草汤及其拆方各组治疗慢性腰肌劳损的临床疗效，以探 讨加味芍药甘草汤治疗慢性腰肌劳损的可能作用机理。方法：临床研究选取慢性腰 肌劳损肝脾两虚证患者 152 例，随机分为加味芍药甘草汤组（治疗组）38 例、拆方 1 组（对照Ⅰ组）38 例、拆方 2 组（对照Ⅱ组）38 例、拆方 3 组（对照Ⅲ组）38 例， 每组服药 4 周，治疗 4 周后对患者症状、体征积分、VAS 评分、中医伴随症候积分 进行评估，对比分析 4 组临床疗效。P＜0.05 为差异有显著性。结果：四组患者治疗 4 周后总疗效比较，治疗组总有效率为 93.94%，对照Ⅰ组总有效率为 75.76%，对照 Ⅱ组总有效率为 77.14%，对照Ⅲ组总有效率为 61.76%，4 组间差别有统计学意义(P ＜0.05)，显示四组均可明显缓解患者症状，改善患者腰部功能。治疗组患者 4 周后 症状、体征积分、VAS 评分同对照Ⅰ组、对照Ⅱ组和对照Ⅲ组相比较，差别均有统 计学意义(P＜0.05)。在治疗期间，未见明显因药物使用引起的不良反应。结论：加 味芍药甘草汤治疗慢性腰肌劳损的疗效优于 3 个拆方对照组，尤其对患者腰部疼痛、 酸困、活动功能等症状体征改善明显。但其作用机制及远期疗效尚有待于通过进一 步实验研究和临床观察来验证和阐明。 关键词：慢性腰肌劳损；加味芍药甘草汤；复方拆方；临床研究 新疆医科大学医学硕士学位论文 Clinical study on compatibility and dismantlement of Jia Wei ShaoYao Gan Cao decoction for chronic lumbar muscle strain Postgraduate:Tang Xinrong Supervisor: Prof. Lu Faming Abstract Objective: To observe Jia Wei ShaoYao Gan Cao decoction and its Separated prescription for chronic lumbar muscle strain of clinical efficacy, and explore the treatment of Jia Wei ShaoYao Gan Cao decoction on the possible role of chronic lumbar muscle strain. Method: The 152 cases of chronic lumbar muscle strain patients that consistent with selected standard were randomly divided into Jia Wei ShaoYao Gan Cao decoction group (treatment group) 38 cases, Separated prescription groupⅠ (control group Ⅰ) 38 cases, Separated prescription group Ⅱ (control group Ⅱ) 38 cases and Separated prescription group Ⅲ (control group Ⅲ) 38 cases, each taking four weeks, The course of treatment were four weeks, To assessment symptoms and signs integral, VAS score, symptom score accompanied by traditional Chinese medicine to assess the comparative analysis of 4 clinical efficacy. P ＜ 0.05 for the difference was significant.Results: Four groups after 4 weeks of the treatment, the total efficiency of groups was 93.94%, 75.76%, 77.14%and 61.76% respectively, difference among the four groups was significant (P＜0.05),shows that four groups