加味苇茎汤对慢性阻塞性肺疾病急性加重期的临床疗效观察及对il8的影响-中医内科学专业论文.docxVIP

The The Clinical Effect Research and Influence and Meanings to Il-8 of the Weijing Soup to AECOPD Specialty：Internal Medicine ofTraditional Chinese Medicine Author：zhangjunhong Tutor：．Professor Liu Xiaohong oBJE(]1VE The aim of the study was to assess the clinical effect and the influence and meanings to II-8 of the Weijing Soup to chronic obstuctive pulmonary disease in acute exacerbation． Ⅲ汀HoDS 60 patients with mild or moderate AECOPD according to the retention of Obstruction of Lung by Phlegm and heat syndrome in TCM were selected from the outpatlent clinic．Patients were randomly assigned to the treating group(group T)or to the control group(group C)on a single—blind basis．Group T was treated by Weijing soup combination with routine westem medicine for 10 days and group C was treated only by routine westem medicine． Comparing the clinical symptom，IL一8，lung function，blood gas analysis of the patients with mild or moderate COPD in acute exacerbation condition according to the Obstruction of Lung by Phlegm and heat syndrome in TCM． RESULTS As to syndrome curative effect the effective rate was 90％but group C was 73．33％．They are has significant difference(P0．05)． Main syndrome had been improved significantly in group T(P0．01)which has significant difference compared with group C(P0．01或PO．05) After the study period，FEVI of has significant differences in group T (P0．05)but not in group C．There were no significant differences in FEVI％ results in either group．But from the result we could know that FEVI and FEVI％ in two group were ascending slightly after the period，while they are in evidence in group T． As As for the result of blood gas analysis，group T and group C could both improve the P02 and reduce the PC02．And there was significant difference in group T compared with group C(PO．05)about anoxia and carbon dioxide retention， According to IL一8，there was significant difference in two group(PO．01)．There was significant difference compared group T with group C after