加减小柴胡汤治疗糖尿病下肢血管病变的临床观察-中医内科学专业论文.docxVIP

中文摘要 [目的]观察血糖、糖化血红蛋白、ABI 指数及中医症候积分的变化情况，分 析加减小柴胡汤治疗 2 型糖尿病周围 血管病变的临床疗效。并探讨糖尿病周围 血管病变的病理机制，为临床治疗提供科学理论依据。 [方法]将 60例2 型糖尿病下肢血管病变患者随机分为治疗组(30 例)和对照 组(30 例);对照组采用控制血糖的糖尿病的基础治疗,治疗组在此基础上,加用加 减小柴胡汤。治疗 3 月后,观察 2 组血糖、糖化血红蛋白、ABI 指数及中医症候 积分的变化情况并做肝、肾功能检查，进行统计分析，判断疗效及用药安全性。 [结果]加减小柴胡汤组较对照组能有效改善患者血糖水平，降低患者糖化血 红蛋白含量，改善患者 ABI 指数，同时明显缓解患者糖尿病下肢血管病变引起的 相关症状。治疗前后患者的肝、肾功能无明显变化，具有良好的疗效和安全性。 [结论] 加减小柴胡汤对 2 型糖尿病下肢血管病变具有较好的临床疗效，能 有效改善患者血糖、糖化血红蛋白、ABI 指数及中医症候。 [关键词]加减小柴胡汤；2 型糖尿病;周围血管病变 To add and subtract small entrapement decoction in the treatment of diabetes clinical observation of the extremities vascular lesions Abstract [Objective] glucose, glycated hemoglobin, ABI index and the change points TCM symptoms, plus reduce the Bupleurum Decoction of type 2 diabetes the clinical efficacy of diabetic angiopathy. Diabetic peripheral v diabetic angiopathy and explore the pathological mechanism for providing scientific theoretical basis for clinical treatment. [Method] 60 atients with type 2 diabetes, peripheral peripheral were randomly divided into treatment group (30 cases) and control group (30 cases); control group were the basis for diabetes control blood sugar treatment group on this basis, plus Add reduced Chai Hu Tang. Month after treatment was observed 2 blood glucose, glycated hemoglobin, ABI index and the change points TCM symptoms and do liver and kidney function tests were analyzed to determine the efficacy and drug safety. [Results] Bupleurum Decoction plus reduced compared with the control group of patients can improve blood glucose levels and lower glycosylated hemoglobin levels in patients, improve patient ABI index, while significantly ease the patients due to diabetic peripheral diabetic angiopathy-related symptoms. Before and after treatment in patients with liver and renal function had no significant change, with good efficacy and safety. [Conclusion] Bupleurum Decoction plus reduced peripheral diabetic angiopathy in type 2 diabetes have better clinical efficacy, can improve