加味建瓴汤治疗原发性高血压的临床研究-中西医结合临床专业论文.docxVIP

黑龙江中医药大学硕士学位论文摘 黑龙江中医药大学硕士学位论文 摘 要 目的：观察加味建瓴汤治疗原发性高血压中医证属肝肾阴虚、 肝阳上亢患者的临床疗效，明确其机制。 方法：将90例原发性高血压患者用单盲法随机分为中药组： 给予加味建瓴汤，每日一剂，分早晚两次口服。四药组：给予依 那普利，日两次口服，每次10mg。‘中西药组：给予加味建瓴汤， 每日一剂，分早晚两次口服；依那普利，日两次口服，每次1 0rag。 疗程为～个月，检测三组患者治疗前后动态血压、血糖、血脂、 中医症状疗效的变化，评价加味建瓴汤治疗原发性高血压的临床 疗效。 结果：在动态SBP、DBP改善方面：治疗后三组间比较，中 西药组血压改善优于西药组及中药组(P0．05)，西药组与中药组 比较无显著性差异(P0．05)。三组患者血压同治疗前比较有硅著 性差异(P0．05)。在血脂改善方面：治疗后三组间比较，中药组 血脂改善优于西药组(P0．05)，中西药组优于西药组(P0．05)， 中西药组与中药组比较无显著性差异(P0．05)；中药组及中西药 组同治疗前比较有显著性差异(P0．05)。在血糖改善方面：治疗 后三组间比较，中药组血糖改善优于西药组(P0．05)中西药组 优于西药组(P0．05)，中西药组与中药组比较无显著性差异 (P0．05)；中药组及中西药组同治疗前比较有显著性差异 (P0．05)。在中医症状改善方面：中西药组总有效率高于其它两 组(P0．05)。 结论：加味建瓴汤能明显改善原发性高血压患者的血压、m 糖、血脂，并能改善症状。 关键词：建瓴汤 原发性高血压 中西医结合治疗 ABSTRACTObject：To ABSTRACT Object：To verify the clinical curative effect of JianLingTan2 treating primary hypertension and clear its mechanism． Method： 90 patients were dicided into three groups at random according to the single blind law．Traditional Chinese medicine group．west；rn medicine group，Chinese and western medicine group．which were given JianLingTang，ACEI，JianLingTang and ACEI respectivelv．A month was curative period．The blood pressure，blood sugar，bloo‘d lipid and sign before and after curation were determined to appraise the clinical curative effect of JianLingTang．Result：Compare the improvent of blood sugar，blood lipid of three groups after curation，we find traditional Chinese medicine group SUperior to western medicine group(P0．05)；Chinese and western medicine group superior to western group(P0．05)；between the traditional Chinese 。medicine group and Chinese and western medicine，difference was not significant(P0．05)；traditional Chinese medicine group and Chinese and western medicine grouD had significent difference after curation(P0．05)；in the improvement respect of DBP after curation，Chinese and western medicine superior to western medicine group and traditional Chinese medicine group(P0．05)；and western medicine group didn’t have significant difference with traditional Chinese m