藿苏清热颗粒药效学研究及对幼年大鼠长期毒性研究-中药学专业论文.docxVIP

山东 山东 中医药大 学 2 009 届 硕 士 学位 论 文 a n d a d e n o v ir u s w e re sig n if ic a nt ly in h ib ite d .T O x ie lo g y stu d y : T h e f o o d 一in t a k e a n d th e a c tio n o f e v e r y g ro u P w a s n o r m a l d u r in g a d m in ist at io n ，a n d th e b o d y w e ig h i w a s g r o w t h ，b u t th ere w as n o d iffe ren ee b etw een eXP erim ental grouP an d control grou P 于 0 .0 5). T h e b lo o d u rea n itro g e n o f larg e d o se gro uP wa s h ig h e r th an th e c o n tro l g ro u P in th e e n d o f th e adm in istratio n an d restoration stage (P 0 .0 5). T h e rest in d ieatr ix o f b lo o d seru nn b io ch em ies an d h em ato lo gy w as n orm al，th ere’s n o diffe ren ce in gro即 5 com P arison 田 0 .0 5).T h e m ajor o r g a n su rf ac e o f t h e ra ts w a s sm o o th a n d g lo s sy ，a n d th e rd s n o a d h e re n e e a n d c o n g e stio n . T h e w e ig h t a n d e o e f fl c ie n i o f th e o rg a n w a s n o r m a l， th e r e’s n o d if fe re n e e in g ro u P s com P arison 口 0 .0 5). In th e en d o f the ad m in istration .an d resto ration stage，the org an o f th e lo w 一d o se g ro u P a n d th e e o n iro l g ro u P w a s n o r m a l. T h e en d o f t h e a d m in istr at io n sta g e ，th e t0 X ic rea c tio n W a S aP P e a re d to k id n e y in th e m id d lo d o se g ro u P a n d th e h ig h -d o se g ro u P ，In th e e n d o f t h e re sto ra tio n sta g e ，th ere ’s 1/ 1 0 still n o re tu m . C o n elu sion : T h e P h an n aco d y n am ie stu d ies h av e sh own that P art icles H o ssu Q in gre sigi fieant ant iP y retie，an a堪esie，ant i一in fiam m atory an d in v itro，in v iv o an tib aeterial an d 抓 iv ira l a c tiv ity . C lin ic a l stu d ie s h a v e sh o w n th a t t re a tm e n i o f e h ild re n w it h E x o g en o u s P art ieles H o ssu Q in gre fev er，T C M are rel