喜炎平治疗小儿轮状病毒性肠炎的随机对照研究.docVIP

喜炎平治疗小儿轮状病毒性肠炎的随机对照研究 岳阳县中医院儿科湖南岳阳414100 【摘要】目的探讨喜炎平治疗小儿轮状病毒性肠炎的疗效。方法选取2014 年1月?2016年4月间我院收治的小儿轮状病毒性肠炎患者80例作为研究对象， 随机分组，对照组40例给予利巴韦林注射液，实验组40例给予喜炎平注射液, 对比两组患者的临床症状及治疗效果。结果实验组患儿治疗时间、止泻时间、 总疗程均短于对照组，1.不良反应发生率为10%,显著低于对照组27.5%,两组 差异具有统计学意义(P0.05);实验组患儿治疗总有效率为95.00%,对照组为 80.00%,实验组显高于对照组，差异显著(P0.05)。结论喜炎平治疗小儿轮 状病毒性肠炎的效果显著，具有缩短治疗时间，降低不良反应发生率，提高治愈 有效率等优势，值得在临床医学推广。 【关键词】喜炎平；小儿轮状病毒性肠炎；临床疗效 【Abstract 】objective to explore xi phlogistic curative effect of treatment of infantile rotavirus virus enteritis. Methods from January 2014 to April 2014 of our hospital between 80 patients with infantile rotavirus virus enteritis as the research object, a randomized, control group 40 cases give ribavirin injection, the experimental group 40 cases give xi ping injection, compared two groups of patients with clinical symptoms and treatment effect. Results the experimental group with treatment time，time of diarrhoea，total course are shorter than the control group， and the incidence of adverse reactions was 10%， significantly lower than the control group 27.5%，the difference between the two groups have statistical significance (P lt; 0.05)； Treatment the total effective rate was 95.00% in the experimental group children，and the control group was 80.00%, the experimental group significantly higher than that of control group, significant difference (P lt; 0.05) . Conclusion xi phlogistic flat for the treatment of infantile rotavirus virus enteritis， shorten the treatment time，reduce the incidence of adverse reactions, improve the cure efficiency and other advantages，is worth popularizing in clinical medicine. 【Key words 】xi phlogistic flat； Infantile rotavirus viral enteritis； Clinical curative effect 小儿轮状病毒性肠炎(秋季腹泻)是儿科疾病中常见的消化道传染性疾病之一, 该病多发于秋冬季节［1】。该病是由于小肠上皮被轮状病毒侵犯，使得上皮细胞 出现坏死甚至脱落，造成肠道分解双糖和吸收水分受到阻碍，使肠液的渗透压升 高，导致患者大便呈无色水样或蛋花汤样，没有腥臭味，但有少许粘液［2】。轮 状病毒性肠炎的传染途径除了经粪、口传播外，还可能以气溶胶形式通过呼吸道 感染他人，因此，家长应及早发现、及吋就诊，确保患儿接受相关治疗。传统的 抗生素治疗轮状病毒性肠炎效果不显著，还可能会加重腹泻，因此，寻找一种新 型H有效的治疗方法成为医学界关注的重点。我院选用喜炎平治疗小儿轮状病毒 性肠炎，