慢性马兜铃酸肾病中医证候学研究-中医内科学专业毕业论文.docxVIP

慢性马兜铃酸肾病的中医证候学研究中文摘要 慢性马兜铃酸肾病的中医证候学研究 中文摘要 本课题在中医理论指导下，进行了慢性马兜铃酸肾病的中医证候学研究。希 望通过该研究，把握本病发展的基本规律，深入探讨本病病因病机，为临床治疗 提供指导。 论文主要包括文献综述和临床证候学研究两部分。 文献综述主要包括马兜铃酸肾病的概念、历史、病因学、发生机制、临床表 现、分型、诊断、治疗几方面，及马兜铃酸的毒性、含有马兜铃酸的中药、中药 配伍应用对其肾毒性的影响等内容。并对目前研究做了简单评述与展望。 临床证候学研究部分，观察慢性马兜铃酸肾病患者44例，根据既有慢性肾 功能衰竭中医证候诊断标准，按症状不同程度评分，统计根据Ccr不同分期各种 症状及证型出现的概率及总出现率，并进行比较。结果：慢性马兜铃酸肾病随病 情发展，正虚证候愈甚，邪实证候愈盛。一般慢性肾功能不全常见的脾肾气虚之 本、血瘀湿浊之标在CAAN依然存在，不同的是，阳虚与血瘀症状出现早而重， 在CAAN发病过程中占有重要地位。 通过以上研究，认识到慢性马兜铃酸肾病中医证候学具有一般慢性肾功能不 全的共性及特殊性。同时对其病因病机及治法进行了探讨，提出到治疗上应注重 其不同的病机特点，选择相应治疗方法，以更好地防治马兜铃酸肾病。 主题词：马兜铃酸肾病慢性中医证候 英文摘要Abstract 英文摘要 Abstract Study the traditional Chinese medical syndrome of chronic aristolochic acid nephropathy(CAAN) This study was under the guidance of traditionaI Chinese medical theory．to explore the charactelistics oftraditional Chinese medical(TCM syndrome)syndrome Though the study,we hope hold the basic rules ofCAAN，to discuss the and pathogenesis ofCAAN．then guide clinical therapy The thesis summarizes including two pans，review and clinical study the TCM syndrome The review part includes AAN concept，history,etiology,pathogenesis，clinical characters，types，diagnosis and treatment of AAN It also includes the toxicity of aristolochic acid(AA)，the traditional Chinese herbs eomaining A丸the influence the renal toxicity ofusing Chinese herbs cooperatively．At the last part ofthe review， we remarked modem study and discussed its outlook In the clinical study part，we observed 44 CAAN patients We graded them according to vadous degrees of their symptoms，based the diagnostic standard of the chronic renal thilure Wj evaluated the arisen of every symptom and every type according the different stages of Ccr．and compared them Results：With the development of the disease，the symptoms became more severely．In general chronic renal failure(CRF)，the tip is spleen and kidney qi deficiency,the is blood stasis and dampness These characters still exist in CAAN．Differently,yang deficiency and blood stasis symptoms appeared early