顺德地区EB病毒感染现状及影响因素分析.docVIP

顺德地区EB病毒感染现状及影响因素 分析 田娜娜潘建南周成宇罗美华吕伟标麦如蓝錘 艳晖刘丽于新发 广东药科大学公共卫生学院 摘要： 目的了解顺德地区人群中EB病毒的流行状况及EB病毒感染的影响因素。方法 于2015年羊月对顺德地区大良、陈村、杏坛三个镇17 727名居民进行问卷调 查，采用酶联免疫吸附法检测EB病毒核心抗体TgA (NAl-TgA)、EB病毒衣壳抗 体IgA (VCA-IgA)水平。采用非条件Logistic回归探讨EB病毒感染的影响因 素。结果 共计纳入17 581人。EB病毒NAl-IgA、VCA-IgA阳性率分别为3. 23% 和6.76%。EB病毒感染率为9.49%。男性的EB病毒感染风险高于女性，0R值为 1. 15 (95%01.04\ 28);与〈40岁年龄组比较,40“9岁年龄组感染风险降低 (0R二0.86;95%CI二0.731 01),而50岁以后随年龄增长，感染风险增加；与小学 及以下文化程度者相比，文化程度高者感染风险降低;吸烟者与非吸烟者相比， 其感染风险增高(0R=l. 19;95%CI=1.0r. 39)。结论 顺德地区男性EB病毒感染 风险高于女性，年龄与EB病毒感染风险呈“V”型关系，高文化程度是EB病毒 感染的保护因素，吸烟可能是EB病毒感染的危险因素。 关键词： EB病毒;EB病毒核心抗体IgA; EB病毒衣壳抗体IgA;危险因素; 作者简介：丁?新发。E-ina订:yuxfa@126. com 收稿日期：2017-01-12 Analysis on the infection situation and influence factors of EB virus in Shunde Region 17ANNa-na PAN Jian-nan ZHOU Cheng-yu LUO Mei~hua LV Wei-biao MA[ Ru-bn GAO Yan-hui LIU Li YU Xin-fa School of Public Hea1th, Guangdong Pharmaceutical University; Shunde Hospital of Southen Medical University; Abstract： Objective To learn about the epidemic situation and influencing factors of Epstcin-Barr virus (EBV) infcction in the population of Shundc region. Methods Questionnaire survey was conducted on 17 727 residents of Daliang, Chencun and Xingtan town in Shunde region from April 2015 to June 2015. The level of nuclear antigen-1 IgA (NAl-IgA) and viral capsid antigen IgA (VCA-TgA) of EB virus were exam ined by en zyme-lin ked i mm uno assay (ELTSA). The unconditioned logistic regression was conducted to explore the influence factors of EB virus infection. Results A total of 17 581 people were selectecL The positive rate of NAl-IgA and (VCA-IgA) of EB virus were 3.23%and 6.76% respectively. The infection rate of EB virus was 9.49%. Men hove a higher risk of EB virus infection than women with OR二 1. 15 (95% CI二 1. 04T. 28) ? Compared with the group of age below 40 years old, age between 40 to 49 reached a lower risk with OR二0.86 (95% CI=0. 73-1. 01), while after 50 years old, the rate of infection increased continuously. Moreover, resi