急性粒细胞缺乏症68例患者的治疗体会.docVIP

急性粒细胞缺乏症68例患者的治疗体会 贵州省六盘水市人民医院肿瘤血液科 553001 目的研究急性粒细胞缺乏症的临床治疗。方法选我院于2010年5月 至2015年1月期间收治的68例急性粒细胞缺乏症患者，用随机数字表法将其分 为实验组和对照组两组，分别为34例。实验组进行升白细胞药联合重组人粒细 胞集落刺激因子(RhG?CSF)治疗以及病因治疗，同时对患者实施全环境保护， 对照组的治疗方式与实验组相同，但没有全环境保护。然后分析比较两组的的治 愈率以及感染率。结果实验组的感染发牛率为8.82%,对照组则为79.4%,两 组比较有显著差异(chi;2二34.36, P0.05)；实验组治愈率为94.12%,而对照 组是70.59%,两组相比较，差异具有统计学意义(chi;2=6.48, P0.05)。结论 对于急性粒细胞缺乏患者，在实施全环境保护的条件下，临床治疗以口服升白细 胞药联合应用rhG-CSF及并用病因治疗等综合方法疗效更好。 关键词急性粒细胞缺乏症；全环境保护；RhG-CSF Experienee of treatment for the 68 cases of acute agranulocytosis Abstract: Objective: To study the clinical treatment of acute agranulocytosis .Methods: Choose 68 cases of patients with acute agranulocytosis who admitted in our hospital during the period of May 2010 to January 2015 , with the method of random number table ,they were divided into experimental group and control group, and 34 cases in each group respectively.For experimental group,we treated patients with drugs which could raise white blood cell and human granulocyte colony stimulating factor (RhG CSF) combining therapy for pathogeny’at the same time , treatment of all-round envir on mental protection also was implemented on patients , the treatment was control group was the same as the experimental one, except the all-round environmental protection.Then analyze and compare the infection rate and cure rate of two groups .Results: The infection rate of experimental group was 8.82%,while the control group is 79.4%, comparing the two groups,there was significant differenee (chi;2= 34.36, Plt;0.05),cure rate of experimental group was 94.12%, while the control group was 70.59%, compared two groups, there was statistically sign讦icant differenee (chi;2=6.48, Plt;0?05).Conclusion: For patients with acute agranulocytosis, under the condition of the implementation of all environmentai protection, clinical treatment with oral drugs which could raise white blood cell level for human, combining the use of rhG CSF and therapy on the etiologies and comprehensive methods, wh