老年性白内障晶体核硬度及相关因素的研究-眼科学专业论文.docxVIP

老年性白内障晶状体核硬度及其相关因素的研究 老年性白内障晶状体核硬度及其 相关因素的研究 (摘要) 目的检测老年性白内障核硬度及其相关的因素。方法50岁以 上老年性白内障47例、47只眼。术前按LOCsII将其散瞳分类。 将白内障囊外摘出的晶体核称净重，测量核的中心厚度和直径后， 用一测定穿透力的装置，测出晶状体的硬度。多元回归分析晶体 硬度与年龄、核颜色、发病时间等因素的关系。结果不同级别 的核所记录的图形不同，最大力位于核中心。穿透I级核所需的 平均力是O．51±0．29牛顿(N)，II级核为1．41±O．35N，1V级核增 加到2．96±O．62N，IV级核所需的平均力是I级核的6倍。回归分 析85％的核硬度与颜色和混浊度有关。皮质及后囊混浊不影响核 硬度。长期糖尿病和高度近视眼Ⅳ级核的频度增加。核颜色与核 的重量(产0．4565)、直径(FO．5263)、厚度(r=0．5552)呈正相关性 (P0．001)，而年龄只与重量(F0．3239)有较弱的相关性(P0．05)。 结论老年性白内障核颜色是判断核硬度、直径和厚度的最可靠 指标，本结果有助于手术医生计划小切口和超声乳化手术。 关键词老年性白内障核硬度相关因素 一l一 THE THE NUCLEAR HARDNESS AND ASSOCIATED FACTORS OF AGE—RELATED Abstract Purpose To determine the nuclear hardness and associated factors of age-related cataract．Methods Forty·seven eyes of 47 patients aged50 years with age· related cataracts were studied．The opacity of lenses were assessed and classified by the LOCS II pre·operatively．The lens nucleus obtained during ECCE were measured．By means of a fine conical probe and dynamometer,the resistance tO penetration of different lens layers Was transferred to electric signal and recorded by a function recorden nle hardness tO the penetration of different lens layers was calculated．Multivariate regression analysis was applied to the parameters including age of patients， color of nucleus，duration of symptoms and other factors． Results The drawing of nucleus hardness of different grades was different．111e most hardness of nucleus Was located in the nucleus center．The mean force required to penetrate the lens Was O．51±0．29 Newtons(N)for grading I and 1．41 ±O．35N for grading II：it increased to 2．964-0．62N for grade[11．There WaS a six- fold difference in mean force between the grade I color group and gradeIV color group．Multi—variant analysis of the data showed that 85％of the variation in hardness could be explained in terms of color and opacity．The patients with the myopic eyes and diabetics had increased incidence of gradinglV nuclear sclerosis． Regression analysis revealed a positive correlation between nucl