神经精神狼疮中甲泼尼龙琥珀酸钠、环磷酰胺、甲氨蝶呤穿透血脑屏障的能力.ppt

主要参考文献 1 Sciascia S,?Bertolaccini ML,?Baldovino S,?Roccatello D,?Khamashta MA,?Sanna G. Central nervous system?involvement?in?systemic?lupus?erythematosus: Overview on classification criteria. Autoimmun Rev. 2013 Jan;12(3):426-9. 2 Unterman A,?Nolte JE,?Boaz M,?Abady M,?Shoenfeld Y,?Zandman-Goddard G. Neuropsychiatric?syndromes in systemic lupus erythematosus: a meta-analysis. Semin Arthritis Rheum. 2011 Aug;41(1):1-11. 3 Alkhotani A. Neuropsychiatric lupus. Sultan Qaboos Univ Med J.??2013 Feb;13(1):19-25.? 4 ACR Ad Hoc Committee on Neuropsychiatric lupus. The American College of Rheumatology and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum 1999;42:599-608 5 Abdel-Nasser AM, Ghaleb RM, Mahmoud JA, Khairy W, Mahmoud RM. Association of anti-ribosomal P protein antibodies with neuropsychiatric and other manifestations of systemic lupuserythematosus. Clin Rheumatol 2008;27:1377-85. 6 Avcin T, Benseler SM, Tyrrell PN, Cucnik S, Silverman ED. A follow up study of antiphospholipid antibodies and associated neuropsychiatric manifestations in 137 children with systemic lupus erythematosus. Arthritis Rheum 2008;59(2):206-13. 7 Mok CC, To CH, Mak A. Neuropsychiatric damage in Southern Chinese patients with systemic lupus erythematosus. Medicine (Baltimore) 2006;85(4):221-8. 8 Yu HH, Lee JH, Wang LC, Yang YH, Chiang BL. Neuropsychiatric manifestations in pediatric systemic lupus erythematosus: a 20-year study. Lupus 2006;15(10):651-7. 9 Neuwelt CM. The?role?of plasmapheresis in the treatment of severe central nervous system neuropsychiatric systemic lupus erythematosus. Ther Apher Dial.?2003 Apr;7(2):173-82. 10Yildirim-Toruner?C,?Diamond B. Current?and?novel?therapeutics in the treatment of systemic lupus erythematosus. J Allergy Clin Immunol.?2011 Feb;127(2):303-12;? 11Valesini?G,?Priori R,?Francia A et al. Central nervous system?involvement in systemic lupus erythematosus: a new therapeutic approach with intrathecal dexamethasone and methotrexate. Sp