半月神经节高电压脉冲射频治疗原发性三叉神经痛的疗效().pdf

38 中国疼痛医学杂志Chinese Journal of Pain Medicine 2015, 21 (1) · · doi:10.3969/j.issn.1006-9852.2015.01.009 半月神经节高电压脉冲射频治疗 原发性三叉神经痛的疗效 * 1 1 2△ 1Δ 申 颖 孟 岚 王 涛 罗 芳 1 2 ( 首都医科大学附属北京天坛医院 疼痛中心； 神经外科，北京 100050) 摘 要 目的：探讨半月神经节高电压脉冲射频治疗原发性三叉神经痛的疗效及安全性。方法：60 例 保守治疗无效的原发性三叉神经痛患者随机分为两组，分别接受半月神经节标准电压和高电压脉冲射 频治疗，比较两组的疗效及副作用。结果：术后6 月有效率标准电压组（41% ）明显低于高电压组（69% ） (P = 0.037)；术后1 年有效率标准电压组降至 19%，显著低于高电压组（69% ）(P = 0.000)。两组脉冲 射频治疗后均未发现明显副作用。结论：高电压脉冲射频治疗三叉神经痛患者安全有效，这种非毁损 的技术将为三叉神经痛患者提供又一治疗选择。 关键词 三叉神经痛；治疗；射频；脉冲 THE CLINICAL EFFICACY OF HIGH-VOLTAGE PULSED RADIOFREQUENCY ON GASSERIAN GANGLION FOR TREATING IDIOPATHIC TRIGEMINAL NEURALGIA 1 1 2 Δ 1Δ SHEN Ying , MENG Lan , WANG Tao , LUO Fang （Department of 1Pain; 2Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050 ） Abstract Objective: To investigate the effectiveness and safety of high-voltage pulsed radiofrequency (PRF) on Gasserian ganglion for treating idiopathic trigeminal neuralgia (TN). Methods: Sixty idiopathic TN patients were randomly assigned into two groups (30 in each group), which were treated with CT-guided standard- or high-voltage pulsed radiofrequency of Gasserian ganglion respectively. The efficacy and side effects were compared between two groups after treatment. Results: The effective rates in the standard-voltage and high- voltage PRF groups were 41% and 69%, respectively, at 6 months after operation (P = 0.037). The effective rate in the standard-voltage group was decreased to 19% one year after operation, while in the hig