对比阿立哌唑和奎硫平治疗老年期精神分裂症的疗效与安全性.docx

对比阿立哌卩坐和奎硫平治疗老年期精神分裂症的疗效与安仝件 哈尔滨市第一专科医院黑龙江哈尔滨150056 【摘 要】目的：对比分析阿立哌卩坐和奎硫平对老年精神分裂疾病的治疗效果和 安全性分析。方法：选取本院2015年7月到2015年门月之间接收的老年期精 神分裂症患者50例，随机分为两组，阿立哌呼组和奎硫平组，两组患者具有可 比性。对阿立哌卩坐组患者采用阿立哌卩坐进行治疗，对奎硫平组患者采用⑴奎硫 平进行治疗，在进行10周的治疗Z后，比较两组患者的恢复情况，发生不良反 应的次数和患者的生活质量情况。结果：通过数据收集和评定，可以发现阿立哌 卩坐组和奎硫平组的治疗有效率分别为91.2%和90.5%,两组的疗效无明显差异， 不具有统计学意义(Pgt；0.05)o不良反应的发生次数，阿立哌卩坐组相较于奎硫 平组较少，具有统计学意义(Plt;0.05)o结论：阿立哌啜和奎硫平是目前治疗 老年期⑵精神分裂症疗效较好的药物，两者的治疗效果相差不大，阿立哌卩坐的 使用副作用较小，能有效的提高患者的生活质量。 【关键词】老年期精神分裂症；阿立哌卩坐；奎硫平 Abstract： Objective： A comparative analysis of aripiprazole and quetiapine treatment effect and safety of elderly schizophrenic illness analysis.Methods： patients with schizophrenia received between July 2015 to November 2015 in our hospital 50 cases of old age, were randomly divided into two groups, aripiprazole combination quetiapine group, two groups were comparable.After aripiprazole group were treated with aripiprazole for treatment of patients with quetiapine⑴quetiapine treatment, during 10 weeks of treatment, the recovery of two groups were compared, the occurrenee of adverse reactions the number and the quality of life of the patient.Results： Through data collect!on and evaluation can be found aripiprazole group and quetiapine treatment group response rate was 91.2% and 90.5% respectively, no sign ificant d iff ere nee in efficacy between the two groups is not statistically significant( Pgt; 0.05).The number of adverse reactions, the aripiprazole group compared to less quetiapine group, with statistical significance (P lt;0.05) in.CONCLUSIONS： Aripiprazole and Quetiapine is the treatment of the elderly[2]Schizophrenia better drugs, the therapeutic effect of the two little difference, aripiprazole use fewer side effectst can effectively improve the the quality of life of patients. Keywords： aged patients with schizophrenia； aripiprazole； quetiapine 精神分裂症是在老年群体中较易发作的精神疾病，在精神疾病中是比较 严重的症状，会严重影响患者的生活质量。现在对老年期精神分裂症的发作因素 和诱导原因还不明确，不能采取有效的措施进行防治措施。精神分裂症是一项复 杂的[3]、病程长、致残率高的疾病，对患者的生活、思想和性格都会产生一定 的影