幽门螺杆菌初次治疗失败后的治疗方案.docx

幽门螺杆菌初次治疗失败后的治疗方案 上海市松江区泗泾医院上海201600 【摘 要】目的：探究幽门螺杆菌初次治疗失败后的治疗方案，以供临床参考以 及研究。方法：木次研究对象从2015年6月?2016年4月于我院经胃镜确诊后 幽门螺杆菌初次治疗失败的消化性溃疡患者中选取88例，通过动态化随机分组 的方法将其分为2组，对照组采用枸椽酸钮钾、阿莫西林、甲硝哇进行治疗，观 察组采用埃索美拉哇、阿莫西林、左氧氟沙星进行治疗，探究患者经不同方法治 疗后幽门螺杆菌根除率以及不良反应发牛率的差异性。结果：通过木文研究结果 中可以看出，观察组患者的根除率与对照组患者相比较，并不存在较大差异 (Pgt；0.05),在不良反应发生率的比较中，观察组患者的结果明显低于对照组 患者的结果，Plt;0.05,差异具有统计学意义。结论：幽门螺杆菌初次治疗失败 后采用埃索美拉哇、阿莫西林、左氧氟沙星进行治疗，能够有效缓解患者的临床 症状，对幽门螺杆菌进行根除，从而提高患者的治疗效果，可应用推广。 【关键词】幽门螺杆菌；初次治疗失败；治疗方案 [Abstract] Objective： To explore the initial treatment of Helicobacter pylori treatment regimens after failure, for clinical reference and research. Methods： This study selected 88 cases from June 2015 ? April 2016 in our hospital after initial endoscopic diagnosis of Helicobacter pylori in patients with peptic ulcer treatment failure through dynamic randomization methods will be divided into 2 group, the control group using potassium bismuth citrate, amoxicillin and metronidazole treatment, observation group esomeprazole, amoxicillin, levofloxacin treatment, after exploring different methods of treating patients with H. pylori eradication rate and the differenee between the incidenee of adverse reactions. Results： The results of this study can be seen through the observation group were eradication rates compared to the control group of patients, there is no big differenee (Pgt; 0.05), comparing the incidenee of adverse reactions, the results of the observation group patients the results were significantly lower than the control group of patients, P lt;0.05, the d iff ere nee was statistically significa nt. Conclusion： Helicobacter pylori after initial treatment failure using esomeprazole, amoxicillin, levofloxacin treatment can effectively alleviate the clinical symptoms of H. pylori were eradicated, thereby improving patient outcomes can be applied promotion. 【Key words] Helicobacter pylori； initial treatment failure； treatment 幽门螺杆菌主要是慢性胃炎、消化性溃疡的重要病因，针对其进行 有效清除具有一定的意义⑴，当消化性溃疡患者经过初次治疗根除幽门螺杆菌 失败之后，需要根据患者失败的原因进行