栓塞治疗对改善高龄膀胱癌出血患者生活质量的临床意义-肿瘤防治研究.PDF

378 2015 42 4  Cancer Res Prev Treat,2015,Vol.42,No.4 · · 肿瘤防治研究 年第 卷第 期 doi:10.3971/j.issn.1000-8578.2015.04.013 · · 临床应用 栓塞治疗对改善高龄膀胱癌出血患者生活 质量的临床意义 郭秀英，张炜浩，李保国，刘方，邢文阁，于海鹏，司同国，郭志 Clinical Significance of Embolization on Quality of Life of Elderly Patients with Bladder  Hemorrhage GUO Xiuying, ZHANG Weihao, LI Baoguo, LIU Fang, XING Wenge, YU Haipeng, SI Tongguo, GUO Zhi Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060,China Corresponding Author: GUO Zhi, E-mail: guozh1955@163.com Abstract: Objective To evaluate the feasibility, efficacy and complications of transcatheter arterial   embolization as a palliative measure for the quality of life(QOL) of elderly patients with bladder hemorrhage. Methods We analyzed retrospectively the clinical data of transarterial embolotherapy on 23 elderly patients with bladder hemorrhage from January 2007 to December 2012, 19 patients underwent bilateral embolization and 4 patients underwent unilateral embolization. Post-embolization angiography findings, bleeding control, QOL and complications were assessed. Results The technical success rate was 100%. Hematuria was controlled after the first procedure(1-5d after embolization) in 20 patients(81.7%) and a repeat procedure was succeeded in the remaining three patients. The forward clinical success was 82.6% since late bleeding recurrence occurred 3, 4, 4 and 6 months after operation was reported in 4 patients during the follow-up. The general QOL was significantly improved compared with the preoperative condition(P0.001). No major complicat