多因素介入对糖尿病的影响.pptVIP

Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes G?de, P., Lund-Anderen, H., Hans-Henrik, P., and O. Pedersen N Engl J Med 2008;358:580-91 Diabetes Background In 2005, U.S. prevalence of DM = 20.8 million people or ~ 7% of the population Diabetes Complications Heart Disease – 2-4x death rates vs. adults w/o DM CVA – risk = 2-4x higher vs. adults w/o DM Retinopathy – #1 cause of blindness in adults 20-74 yoa. Nephropathy – #1 cause of CRF Nervous system damage Acute hypoglycemia or hyperglycemia Peripheral vascular disease Complications during pregnancy Steno-2 Study: In