胰岛素抵抗和内皮功能.pptVIP

Insulin Resistance and Endothelial Dysfunction: The Road Map to Cardiovascular Disease Clinical Prototypes: Diabetes Mellitus and Metabolic Syndrome Insulin Resistance and Atherosclerosis Metabolic imbalance - Insulin signaling defects Vascular abnormalities - molecular mechanisms Linkage between metabolic and vascular disease Functional and Structural Vascular Changes Microcirculation and Capillary Recruitment “Superoxide” Generation Theory Atherogenic Lipoproteins Intra-myocellular Fatty-Acyl-Coa Inflammatory Response - NFKβ pathway Relative Risk of CVD in Subjects With and Without Diabet