Nuclear-receptors(核受体))培训课件.pptVIP

INTRACELLULAR RECEPTORS;The intracellular (nuclear) receptor superfamily Steroid hormones, thyroid hormones, retinoids and vitamin D ;Regulation of transcription activity;Intracellular signal molecules small, lipid-soluble molecules such as steroid hormones, retinoids, thyroid hormones, Vitamin D. (made from cholesterol) These molecules diffuse through plasma and nuclear membranes and interact directly with the transcription factors they control.;*;*;Steroid Hormones;;BIOSYNTHESIS OF STEROIDS;Endocrine disruption;Toxicants interact with hormonal system at different levels;biosynthesis and re