免疫化学诊断技术的分类与局限.pptVIP

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免疫化学诊断技术的分类与局限.ppt

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* * * * 11 * * 12 * * 24 * * Here is the current ACS:180 assay menu...a total of 41 assays to date.... arranged in Disease State Groups: -Full Thyroid Function Panel - including 3rd generation TSH and FT3! -Full Fertility Panel - including Estradiol, Progesterone, and Testosterone! -Full Anemia Panel - including B12 and Folate, both serum and red cell! -An impressive Cardiovascular Panel - including CKMB (mass) and Myoglobin, with additional tests in development -Large and growing Oncology panel -The eight most popular Therapeutic Drug Monitoring assays -The first automated assay for a bone resorption marker- DPD! -Total IgE for allergy management -Cortisol - both serum and urine (extracted or non-extracted) * * The ACS:180 was the FIRST fully automated, random access, high throughput immunoassay system available - and it STILL has major advantages over any other system for today’s busy and challenged laboratories. Since its introduction in late 1991, the ACS:180 has been a significant success, worldwide - with over 4000 instrument systems shipped, into 50 different countries, and virtually every U.S. state. Over 650 MILLION tests have been shipped from this facility in support of these installations around the world! The ACS:180 has become the dominant immunoassay system in high volume laboratories, worldwide - due to its impressive test throughput, rapid turnaround time of results, and its ability to consolidate testing workstations. * * * * * * * * * * * * * * * * * * * * * * 时心电图并不能典型归类诊断急性心肌梗塞之困难一半有不稳定胸口窒息痛的病人，入院病人重发梗塞诊断困难引致不能及时诊断AMI 延迟适当的治疗、护理临床需要尽早分辨、准确诊断AMI方法肌肉组织心肌心肌细胞特异性标志肌钙蛋白 I C T 肌钙蛋白 I 释放入血 c 心肌坏死（氨基酸顺序40％差异）心肌细胞肌红蛋白肌酐激霉MB 心肌坏死释放入血（含量大）血液浓度明显升高 (CK-MB) 6 5 4 3 2 1 0 4 8 12 16 20 24 48 72 96 h 肌红蛋白 CK-MB 肌钙蛋白? 浓度急性心肌梗塞后各项指标变化肌红蛋白升高高峰回落肌酐激霉MB 肌钙蛋白I 1-2 h 4-8h 6-8h 5-12h 10-24h 12-24h 18-30h 48-72h 5-7d 肌红蛋白的临床意义早期诊断特异性低灵敏度高急性心梗后最早(1-2h)出现的标记最早能排除非急性心梗阴性预测率为 99 % 体内周期短，对