血吸虫新(.5)教材课程.pptVIP

血吸虫(blood fluke)裂体吸虫(schistosome);分类;主要虫种： 日本血吸虫(Schistosoma japonicum) 曼氏血吸虫(Schistosoma mansoni) 埃及血吸虫(Schistosoma haematobium) 间插血吸虫(Schistosoma intercalatum) 眉公血吸虫(Schistosoma mekongi) 马来血吸虫(Schistosoma malayensis) ;日本血吸虫 Schistosoma japonicum;在柬埔寨、老挝和泰国发现的湄公血吸虫，过去认为系日本血吸虫的一株，1978年Voge等根据其虫卵比日本血吸虫的四个地理株的虫卵小，中间宿主为开放拟钉螺(Tricula aperta)，开放前期也较其他四个地理株为晚等而定为湄公血吸虫。在马来西亚的类日本血吸虫已确定为马来血吸虫( S. malayensis, Greer et al,1988)，其中间宿主为卡波小罗伯特螺 (Robertsiella kaporensis) 及吉士小罗伯特螺(R. gismanni)。 ;Schistosoma japonicum Katsurada,1904 ;Schistosomiasis japonica was first mentioned by Fujii, a Japanese physician, in 1847 Baelz (1883) made the first epidemiologic survey in Okayama Prefecture, Japan, but attributed the disease to Clonorchis sinensis Yamagiwa (1890), Kurimoto (1893), and especially Fujinami (1904) found eggs of the parasite in various organs of patients and ascribed the etiologic role in the infection to the eggs. Kasai (1903） first found the eggs in feces. ;Fujinami（l904) first found the female worm in the portal vein. Katsurada (1904) first described the adult worms, obtained from infected dogs and cats, and assigned to the parasite a new specific name, i.e. ,japonicum. Logan (1905） diagnosed the first case in China. ;The experimental work of Fujinami (1909), Miyagawa (1912-1913), and Miyairi and Suzuki (1913-1914) furnished proof for the life cycle of S. japonicum and provided a basis for Leipers work on the blood flukes in Egypt (1915-1918）. Details of the biology and pathogenesis of S. japonicum were described by Faust and Meleney in 1924. This infection is confined to areas in the Far East .;In Japan five relatively small foci are involved. In China practically the whole of the Chang Jiang（Yangtze) Basin is studded with endemic foci from western Sichuan to the sea. In addition, the coastal area from northem Jiangsu Province to Quangdong, including river valleys extending far inland, the large island of Hainan off the coast of southeastern China, and the Meko