* * * * * * * * * Findings The overview of placebo-controlled trials of ACE inhibitors (four trials, 12 124 patients mostly with coronary heart disease) revealed reductions in stroke (30% [95% CI 15–43]), coronary heart disease (20% [11–28]), and major cardiovascular events (21% [14–27]). The overview of placebo-controlled trials of calcium antagonists (two trials, 5520 patients mostly with hypertension) showed reductions in stroke (39% [15–56]) and major cardiovascular events (28% [13–41]). In the overview of trials comparing bloodpressure- lowering strategies of different intensity (three tr
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