中枢神经系统影像检查方式总论.pptVIP

NORMAL T-SPINE MENINGIOMA DEGENERATION CHANGE IN VERTEBRAL BODY 谢谢 * The effect of diffusion gradients on spin-echo images is shown in the opposite frame. Tissues with highly mobile water, such as cerebrospinal fluid (CSF) (strong diffusion) appear dark on images acquired in the presence of strong diffusion gradients, reflecting the dephasing of the contributing spins. Signal intensity on a diffusion-weighted image is defined by the formula S0, and hence the diffusion-weighted image, still contains contributions from spin density and relaxation times T1 and T2; therefore, the hyperintense lesion on a diffusion-weighted image may reflect a strong T2 effect (T2 shine-through effect) instead of reduced diffusion. * Figure 3. Axial diffusion-weighted (z sensitizing direction) multishot echo-planar image (800/123) obtained with one signal acquisition and 6-mm section thickness. The hyperintensity involving subcortical white matter and overlying cortex in the left parietal lobe is consistent with subacute infarction (arrow). * 对比剂增强血管成像 MRI对比剂 钆 Gadolinium 螯和物 Gadolinium-DTPA Gd-DTPA 作用：缩短纵向弛豫时间（T1） 在T1WI中使信号强度增加 增强后 增强前 fMRI 功能磁共振成像 Diffusion 弥散成像 Perfusion 灌注成像 BOLD 血氧依赖水平成像 （blood oxygen level dependent) T2 Flair T2 DW Tumor Perfusion BOLD 弥散加权成像Diffusion Weighted Imging ,DWI Brownian motion 水分子的自由运动 所有动能使分子在空间中的移动称为弥散 Apparent diffusion coefficient, ADC 表现弥散常数 DWI是一项基于发现分子水平运动异常的技术 Tissues with highly mobile water (strong diffusion) appear dark on images. 强弥散的组织在DWI中呈低信号。 Tissues with lowly mobile water (weak diffusion) is hyperintensity on images,. 弱弥散的组织在DWI中呈高信号 DWI 弥散加权图像 ACUTE INFARCTION 急性脑梗死的细胞源性水肿（Cytotoxic Edema） 导致了弥散功能的障碍 77-Year-Old Man Who Had Acute Stroke 4 Hours ULTRA-ACUTE INFARCTION DWI T2WI FLAIR Differential old infarction from new onset 血氧依赖水平成像blood oxygen dependent imaging, BOLD 利用脱氧血红蛋白的磁敏感性为基础的磁共振成像技术. 当脑组织兴奋时,局部血流量增加,含氧血红蛋白增加,脱