如何回复SCI期刊给出修改意见精品.pptVIP

CARCINOGENESIS MOLECULAR BASIS OF CANCER DAVID LEWIN MD NANT AND DAD TEL  OVERVIEW BASIC CONCEPTS OF ONCOGENES, TUMOR SUPPRESSOR GENES APOPTOSIS DNA repair telomeres HOW THEY ARE ASSOCIATED WITH MALIGNANCY PROPOSED FUNCTIONS GENETIC ALTERATIONSK ASSOCIATED WITH THEIR ACTIVATION OR LOSS  FUNDAMENTAL PRINCIPLES Non-Lethal genetic damage(Mutations) Acquired Environment (next lecture) Inherited(Germ line) Tumors arise from a single progenitor cell Monoclonal (x-linked isoenzyme Target Genes Proto-oncogenes, TSG, Apoptosis, DNA repair Multistep process  MONOCLONALITY