病理学教学课件：The diseases of digestive system.pptVIP

Chapter 8 The diseases of digestive system 2.Barret esophagus Definition: metaplasia of the squamous eosphageal mucosa to a more protective columnar type because of chronic exposure to gastric secretions Cause: gastroesophageal reflux disease Gross: irregular gastroesophageal junction with tongues of red granular mucosa extending up into the esophagus Increased risk of dysplasia and esophageal adenocarcinoma Esophageal carcinoma Squamous cell carcinoma Epidemiology The most common type of esophageal cancer Malesfemales; age usually50 Risk factors Heavy smoking and alchol use Achalasi