肿瘤学课件 纤维肉瘤.pptVIP

Sushi Sushi Sig- Middle aged, FS, Dalmatian 中年，母犬，大麦町 History- the owners noticed a mass on the thorax and immediately presented to the RDVM. 病史－主人在其胸部曾发现有肿块，立刻去RDVM就诊 Physical exam- mass on the thorax (always measure) 体检－胸部有肿块 Sushi Problem List- 问题列表 SC mass on the thorax 胸部锁骨下有肿块 DD s 鉴别诊断 Diagnostic Plan 诊断计划 Sushi Fine needle aspirate- 细针穿刺 Sushi Diagnosis- Fibrosarcoma 诊断－纤维肉瘤 Plan- 计划 Where do these tumors metastasize to? 这些肿瘤向哪里转移？ Sushi Lungs- 肺 Thoracic radiographs- no evidence of metastasis 胸部X光－无明显转移 What is the main problem with these tumors? 这些肿瘤的主要问题是什么？ Which tests should we perform now? 现在我们该做什么测试？ Sushi Local aggressiveness- 局部侵袭 so we should perform a CT! 所以我们要做CT In many cases, despite no evidence of problems on radiographs, what we see is the “tip of the iceberg” 许多病例中，尽管X光中无明显问题，其实我们看到的只是“冰山一角” Sushi- CT Sushi Based on the CT- the surgery was performed, and clean margins were obtained. 基于CT－进行手术，获得清洁的边缘 Miko Doing fine, BAR. The only abnormality is the mass on the lateral thorax. 一切良好，唯一异常就是在侧胸有一肿块。 Diagnosed at the RDVM with a spindle cell sarcoma ( FNA) 在RDVM诊断为梭形细胞肉瘤(细针抽吸)。 Thoracic radiographs were within normal limits. 胸部X光显示正常。 As there is no evidence of metastasis, we decided to perform a CT prior to surgery. 由于无明显转移，我们决定在手术前进行CT。 Miko Show CT Miko Clearly – in this case- surgery is not an option and would have been a mistake. 很明显－此病例－手术不是一种选择，可能会是一个错误。 The dog is asymptomatic and can continue living until the tumor affects his quality of life. 该犬无症状而且可以一直存活到肿瘤影响到他的生活质量为止。 Incidence and Risk Factors 影响和风险因素 Most sarcomas are solitary in the older dog and cat 大多数老年犬猫的肉瘤都是单一肿瘤 Etiology- sarcomas have been associated with radiation, trauma, foreign bodies, and parasites 病源学－肉瘤常与放射线，外伤，外源异物和寄生虫有关。 Pathology 病理学 Develop from mesenchymal tissues 从间质细胞组织发展而来。 Do not include tumors of hematopoietic or lymphoid origin 不包括造血和淋巴系统起源的肿瘤 Often considered collectively due to their similarity in clinical behavior and similarity in