从普通肝素到磺达肝癸钠肝素类抗凝药物研发历程[宣讲].pptVIP

结 论 Fondaparinux is at least as effective and equally safe as UFH for the initial treatment of PE and as LMWH for the initial treatment of DVT The fondaparinux regimen is a once-daily SC injection without body weight adaptation Will allow for simplified treatment at home 磺达肝癸钠临床循证过程 治疗VTE 治疗DVT和PE REMBRANDT MATISSE-DVT MATISSE-PE 预防VTE 骨科大手术 PENTATHLON PENTATHLON 2000 PENTAMAKS EPHESUS PENTHIFRA PENTHIFRA PLUS 内科患者 ARTEMIS 腹部手术 PEGASUS APOLLO 治疗ACS 治疗NSTEMI和STEMI PENTALYSE PENTUA ASPIRE OASIS 5 OASIS 6 50 000 例患者 NSTE ACS患者，胸部不适24h 至少符合下列3项中的2项：年龄60岁，ST段Δ，心肌坏死标志物 磺达肝癸钠 OASIS5