药物合成反应(闻韧第三版)课后翻译.docxVIP

1、 About 216 –224 g. (1.62–1.68 moles) of powdered anhydrous is added to a 1Lthree-necked flask. 在 1L 的三口烧瓶中加入大约 216-224g(1.62 –1.68 moles) 的无水 三氯化铝。 While the free-flowing catalyst is stirred , 81 g. (0.67 mole) of is added from the dropping funnel in a slow stream over a period of 20 –30 minutes. 自由流 动的催化剂边搅拌边用滴液漏斗缓慢滴加 81g 苯乙酰。 Considerable heat is evolved, and, if the drops of ketone are not dispersed, darkening or charring occurs. 放热反应，假 如滴加的酮不能被分散，就会变黑或是碳化。 When about one-third of the has been added, the mixture becomes a viscous ball-like mass that is difficult to stir. 当三分之 一的乙酰苯