中药治疗呼吸道合胞病毒感染临床疗效观察.doc

中药治疗呼吸道合胞病毒（RSV）感染临床疗效观察 中药治疗呼吸道合胞病毒（RSV）感染 临床疗效观察 专业：中医儿科学 研究生：陈永芳 导师：林东红主任医师 摘要 ABSTRACT 冃的：通过对冬春季呼吸道感染患儿进行呼吸道合胞病毒（RSV-IgM ） 常规检测，对呼吸道合胞病毒（RSV）感染患儿分别予中西药治疗，比较 其疗效，为中药治疗RSV疗效提供客观依据。 方法：严格按照试验病例标准选择呼吸道合胞病毒（RSV）感染患儿 60例，采取 简单随机方法分为治疗组30例，对照组30例。组间一般资 料无显着差异（pgt;0.05）。两组均采用如下治疗，利巴韦林50?：LOOm次, 配成20 mg/ml浓度雾化吸入，日二次，疗程5天；合并细菌感染者加用 抗感染；毛支患儿加用甲基强的松龙l-2mg / kg?d,静脉滴注，日1次， 用3天。酌情加博利康尼1.25?2.5吨/次,沐舒坦7.5-15 mg/次,雾化。治 疗组在此基础上予中药汤剂加减麻杏石甘汤（痰热壅肺型）或加减银翘散 （风热外袭型）化裁治疗，每日1齐I」，疗程5天。比较两组临床疗效，探 讨中药对RSV感染的疗效。 结果：（1）治疗组临床疗效明显优于对照组，其显效率与对照组比较 冇显著差异(PIt; 0.05)o (2)①治疗组发热患儿体温恢复正常时间比对 照组短，两组间比较有极显著性差异(PIt; 0.01) o②治疗组患儿咳嗽、 气喘、肺部体征改善方面优于对照组，两组比较差异显著(P It; 0.05) o 结论：中药治疗RSV感染患儿的临床疗效较为确切，中药治疗确有加 速炎症吸收，缓解症状，缩短病程Z效，尤其退热、止咳平喘明显优于 西药治疗组。主题词：呼吸道合胞病毒(RSV) /药物作用儿童麻杏 石甘汤银翘散 Clinical research of traditional Chinese medicine in treatin呂 infants were infected with respiratory syncytial virus Major: Pediatrics of TCM Postgraduate: chen yong fang Tutor: Vice Prof. Lin dong hong ABSTRACT Objectives:Through a routine RSV check of the flu-infected children in spring and winter, we compare the respective effect of treating the infected children with traditional Chinese and western medicine, and thus provide a objective proof for curing RSV by traditional Chinese medicine. Method: Choose 60 RSV-infected infants according to testing the case standard strictly, take the simple random method to divide into two groups with treating group 30 and control group 30. The general documents have not been showing the differenee (pgt; 0.05) among the groups. We treat the two groups as following: use ribavirin 50?lOOmg / time, atomization sucks, twice a day. Who combi ne bacterial inf ection use additi onal anti?in fection drugs, bronchiolitis infant add and spend glucocorticoid (methylprednisolone Zmg/kg.d, intravenous drip, once a day, use for 3 days?),Terbutaline 1.25-2.5mg / time, chymotrypsin 4000u / time, atomization sucks twice a day together with ribavirin, it is a course of treatment in 7 days. Treat group be give tra